131072-55-4Relevant articles and documents
Five membered ring formation of 2-hydroxyalkyl malonate and acetoacetate derivatives the problem of O-versus C-alkylation
Adams, Elisabeth,Hiegemann, Monika,Duddeck, Helmut,Welzel, Peter
, p. 5975 - 5992 (2007/10/02)
The cyclization reactions of type 32, 34, 36, 37/38 compounds have been studied with the aim of achieving a carbon-carbon bond forming reaction at C-2 of optically active glycerol derivatives as indicated in Scheme 1. In all cases O-alkylation at the proximal CO group has been observed.