13110-37-7

Basic information

• Product Name: N-PENTYL-4-AMINOBENZOATE
• Synonyms: AURORA 1608;AKOS BBS-00007957;N-PENTYL-4-AMINOBENZOATE;N-AMYL 4-AMINOBENZOATE;amylp-aminobenzoate;benzoicacid,4-amino-,pentylester;n-pentylp-aminobenzoate;pentyl4-aminobenzoate
• CAS NO: 13110-37-7
• Molecular Formula: C₁₂H₁₇NO₂
• Molecular Weight: 207.27
• EINECS: 229-408-9
• Mol File: 13110-37-7.mol
• Article Data: 4

Chemical Properties

• Melting Point: 51-53°C
• Boiling Point: 346.3°C (rough estimate)
• Flash Point: 133.8°C
• Appearance: /
• Density: 1.0681 (rough estimate)
• Vapor Pressure: 4.55E-05mmHg at 25°C
• Refractive Index: 1.5220 (estimate)
• PKA: 2.39±0.10(Predicted)
• Water Solubility: 39.17mg/L(room temperature)
• CAS DataBase Reference: N-PENTYL-4-AMINOBENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: N-PENTYL-4-AMINOBENZOATE(13110-37-7)
• EPA Substance Registry System: N-PENTYL-4-AMINOBENZOATE(13110-37-7)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 13110-37-7(Hazardous Substances Data)

Usage

General Description

N-PENTYL-4-AMINOBENZOATE, also known as ethyl aminobenzoate or benzocaine, is a local anesthetic and pain reliever commonly used in over-the-counter products such as creams, ointments, and sprays. It works by numbing the skin and mucous membranes, providing temporary relief from pain and discomfort. N-PENTYL-4-AMINOBENZOATE is often used to alleviate symptoms of minor skin irritations, itching, insect bites, and sunburn. It is generally considered safe for topical use when applied as directed, but should not be ingested or used in large quantities as it can cause serious side effects. Overall, N-PENTYL-4-AMINOBENZOATE is a widely used and effective ingredient in various topical pain relief products.

InChI:InChI=1/C12H17NO2/c1-2-3-4-9-15-12(14)10-5-7-11(13)8-6-10/h5-8H,2-4,9,13H2,1H3

Upstream product

• 14309-42-3 pentyl 4-nitrobenzoate 
• 71-41-0 pentan-1-ol 
• 150-13-0 4-amino-benzoic acid 
• 122-04-3 4-nitro-benzoyl chloride 

Downstream Products

• 3529-99-5 4-isothiocyanato-benzoic acid pentyl ester 
• 70925-69-8 pentyl 4-(4-decyloxybenzylideneamino)benzoate 
• 91669-53-3 pentyl 4-(4-hexyloxybenzylideneamino)benzoate 
• 91669-54-4 pentyl 4-(4-heptyloxybenzylideneamino)benzoate 
• 131293-79-3 C₂₆H₂₄ClNO₄ 
• 131293-68-0 C₂₇H₂₇NO₄ 
• 131294-03-6 C₂₈H₂₇NO₆ 
• 117514-84-8 4-(6-Nitro-1,3-dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-benzoic acid pentyl ester 
• 88485-90-9 4-[(Cyano-phenyl-methyl)-amino]-benzoic acid pentyl ester 
• 89685-50-7 pentyl 4-(4-phenylbenzylideneamino)benzoate 
• 70925-65-4 pentyl 4-(4-pentyloxybenzylideneamino)benzoate 
• 91669-51-1 pentyl 4-(4-propoxybenzylideneamino)benzoate 
• 91669-52-2 pentyl 4-(4-butoxybenzylideneamino)benzoate 
• 109044-03-3 N-chloroaceto-4-aminopentylbenzoate 

Relevant articles and documents

Synthesis and phase behaviors of side-chain liquid-crystalline polymers containing azobenzene mesogen with the different length alkyl tail

A series of side-chain liquid-crystal polymers, poly[6-[4-(4′-n-alkyl benzoateazo)phenoxy]-hexylmethacrylate]s (PMAzoCOORm, m = 1, 2, 3, 4, 5, 6, 8, 10, 14, and 18) have been prepared by two synthetic methods. The chemical structure of the monomers was confirmed by 1H NMR and mass spectrometry. The molecular characterizations of the polymers were performed with 1H NMR and gel permeation chromatograph. The phase behaviors of polymers were investigated by the combination of techniques including differential scanning calorimetry, polarized optical microscopy, and small-angle X-ray scattering. For m = 1, 2, 3, 4, 5, and 6, the polymers exhibited a monosmectic A phase in which the smectic layer period was almost identical to the side-chain length. In addition, for m = 2, 3, 4, and 5, they presented the monosmectic C phase in low temperature; moreover, the tilt angle increased from 23.3 to 40.5°. For m = 8, 10, 14, and 18, the polymers showed a bilayer smectic A phase in which the layer spacing was larger than a fully extended side chain but less than two extended chains. On the other hand, for the clearing point, with the increasing of m, it first decreased, and then increased. All of these indicated that the length of alkyl tails played an important role in the phase behaviors of these polymers.

Smectogenic Salts Formed by Combination of Alkyl p-Aminobenzoates and p-Ethyl- or p-Chlorobenzenesulfonic Acid

Two series of smectogenic salts were obtained by combining alkyl p-aminobenzoates with p-ethyl- and p-chlorobenzenesulfonic acids, respectively.The shortest ester alkyl chain required to generate a smectic A phase is nonyl when the former sulfonic acid is employed but the chain may be as short as butyl when the latter is employed.The smectic A-isotropic transition temperature in the second series is significantly higher than that in the first series, indicating that the terminal substituent on the anion is as crucial as that in non-ionic mesogens in determining the mesophase stability. - Keywords: Smectic, alkyl p-aminobenzoates, benzenesulfonates