1311147-09-7

Basic information

• Product Name: N-benzyl-N-(1-methoxy-2,2-dimethylpropyl)-o-deuteriobenzamide
• Synonyms: N-benzyl-N-(1-methoxy-2,2-dimethylpropyl)-o-deuteriobenzamide
• CAS NO: 1311147-09-7
• Molecular Weight: 312.416
• Mol File: 1311147-09-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-benzyl-N-(1-methoxy-2,2-dimethylpropyl)-o-deuteriobenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-N-(1-methoxy-2,2-dimethylpropyl)-o-deuteriobenzamide(1311147-09-7)
• EPA Substance Registry System: N-benzyl-N-(1-methoxy-2,2-dimethylpropyl)-o-deuteriobenzamide(1311147-09-7)

Safety Data

• Hazardous Substances Data: 1311147-09-7(Hazardous Substances Data)

Upstream product

• 4551-39-7 2-deuteriobenzoic acid 
• 4409-84-1 2-deuteriotoluene 
• 95-46-5 2-methylphenyl bromide 
• 67-56-1 methanol 
• 43019-96-1 d₂-benzoyl chloride 
• 1775-74-2 N-(2,2-dimethylpropylidene)benzylamine 

Downstream Products

• 1311147-16-6 2-benzyl-3-tert-butylisoindolin-1-one 
• 1311147-24-6 2-benzyl-3-tert-butyl-7-deuterioisoindolin-1-one 

Relevant articles and documents

Nickel(0)-catalyzed cyclization of N -benzoylaminals for isoindolinone synthesis

A nickel(0) catalyst effectively mediates the cyclization of N-benzoyl aminals in the presence of a stoichiometric Lewis acid. This method enables preparation of a variety of isoindolinones with substitution on the benzoyl fragment and C-3 carbon. This reaction likely proceeds via an α-amidoalkylnickel(II) intermediate, which then may cyclize via either an electrophilic aromatic substitution or an insertion pathway.