1311375-37-7

Basic information

• Product Name: 1-benzyl-5-((tert-butyldimethylsilyloxy)methyl)-5,6-dihydropyridin-2(1H)-one
• CAS NO: 1311375-37-7
• Molecular Weight: 331.53
• Mol File: 1311375-37-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-benzyl-5-((tert-butyldimethylsilyloxy)methyl)-5,6-dihydropyridin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-5-((tert-butyldimethylsilyloxy)methyl)-5,6-dihydropyridin-2(1H)-one(1311375-37-7)
• EPA Substance Registry System: 1-benzyl-5-((tert-butyldimethylsilyloxy)methyl)-5,6-dihydropyridin-2(1H)-one(1311375-37-7)

Safety Data

• Hazardous Substances Data: 1311375-37-7(Hazardous Substances Data)

Upstream product

• 744212-68-8 (±)-1-benzyl-5-(hydroxymethyl)piperidin-2-one 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 1311375-50-4 1-benzyl-5-((tert-butyldimethylsilyloxy)methyl)piperidin-2-one 

Downstream Products

• 1311375-44-6 1-benzyl-5-(((tert-butyldimethylsilyl)oxy)methyl)-3-(6-methoxypyrazin-2-yl)-5,6-dihydropyridin-2(1H)-one 
• 1311375-41-3 1-benzyl-5-((tert-butyldimethylsilyloxy)methyl)-3-(1-methoxyisoquinolin-3-yl)-5,6-dihydropyridin-2(1H)-one 
• 1311375-38-8 1-benzyl-5-((tert-butyldimethylsilyloxy)methyl)-3-(6-methoxypyridin-2-yl)-5,6-dihydropyridin-2(1H)-one 
• 1311375-51-5 1-benzyl-3-bromo-5-((tert-butyldimethylsilyloxy)methyl)-5,6-dihydropyridin-2(1H)-one 

Relevant articles and documents

Core modification of cytisine: A modular synthesis

Getting down to the core: A novel, modular, and more robust synthesis of cytisine, a partial agonist selective for the α4β2 nicotinic acetylcholine receptor, also allows modification of the core structure, as exemplified by the first azacytisine and a cytisine-varenicline hybrid. Key steps include Stille coupling of heteroarylstannanes with a bromolactam motif and an in situ epimerization/alkylative cyclization to complete the tricyclic core (see scheme). Copyright