13114-96-0Relevant articles and documents
The reaction of 2-(acylamino)benzonitriles with primary aromatic amines: A convenient synthesis of 2-substituted 4-(arylamino)quinazolines
Marinho, Elina,Proen?a, M. Fernanda
, p. 1623 - 1632 (2015)
Abstract 2-Substituted 4-(arylamino)quinazolines were prepared from 2-(acylamino)benzonitriles and primary arylamines by refluxing in either ethanol using trifluoroacetic acid as a catalyst or acetic acid. The 2-aminobenzonitrile was acylated by reaction with anhydrides, isocyanates, or ethyl chloroformate at room temperature.
I2-Catalyzed transformation of: O -aminobenzamide to o -ureidobenzonitrile using isothiocyanates
Chaithra, Nagaraju,Gurukiran, Mahesha,Lokanath, N. K.,Mamatha, Mahesha,Mantelingu, Kempegowda,Rangappa, Kanchugarakoppal S.,Shamanth, Sadashivamurthy
supporting information, p. 2678 - 2684 (2020/04/17)
The present work describes an unexpected and unique protocol for the iodine catalysed synthesis of o-ureidobenzonitriles using o-aminobenzamides and isothiocyanates via intramolecular rearrangement. The metal-free route achieved here is insensitive to moisture and applicable to the synthesis of a wide variety of o-ureidobenzonitriles with excellent yields even in a scalable fashion.
Controlling molecular tautomerism through supramolecular selectivity
Epa, Kanishka,Aakeroey, Christer B.,Desper, John,Rayat, Sundeep,Chandra, Kusum Lata,Cruz-Cabeza, Aurora J.
supporting information, p. 7929 - 7931 (2013/09/02)
We have isolated the stable as well as the metastable tautomers of 1-deazapurine in the solid state by exploiting principles of supramolecular selectivity in the context of cocrystal design.
