13127-77-0

Basic information

• Product Name: N,N-bis(2-hydroxyethyl)-p-chloroaniline
• Synonyms: N,N-bis(2-hydroxyethyl)-p-chloroaniline
• CAS NO: 13127-77-0
• Molecular Weight: 215.68
• Mol File: 13127-77-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N,N-bis(2-hydroxyethyl)-p-chloroaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-bis(2-hydroxyethyl)-p-chloroaniline(13127-77-0)
• EPA Substance Registry System: N,N-bis(2-hydroxyethyl)-p-chloroaniline(13127-77-0)

Safety Data

• Hazardous Substances Data: 13127-77-0(Hazardous Substances Data)

Upstream product

• 96-49-1 [1,3]-dioxolan-2-one 
• 106-47-8 4-chloro-aniline 
• 107-07-3 2-chloro-ethanol 
• 75-21-8 oxirane 

Downstream Products

• 1428438-45-2 C₁₈H₁₆ClNO₄ 
• 86396-81-8 6-(p-chlorophenyl)-5,6,7,8-tetrahydro-4H-1,3,6-dioxazocine 
• 106073-45-4 2-methyl-6-(p-chlorophenyl)-5,6,7,8-tetrahydro-4H-1,3,6-dioxazocine 
• 64977-12-4 N,N-bis-(2-bromo-ethyl)-4-chloro-aniline 
• 6636-75-5 4-chloro-N,N-bis(2-chloroethyl)aniline 
• 1190861-65-4 2,2'-(4-chlorophenylazanediyl)bis(ethane-2,1-diyl)dimethanesulfonate 

Relevant articles and documents

Synthesis, crystal structure and biological activity of novel diester cyclophanes

A series of novel diester cyclophanes was synthesized by esterification of 1,2-benzenedicarbonyl chloride with eight different diols under high dilution conditions. The structures of the compounds were verified by elemental analysis, 1H nuclear magnetic resonance (NMR), IR spectroscopy and high resolution mass spectrometry (HRMS). The crystal structures of two compounds were characterized by single crystal X-ray diffractometry (XRD). All the new cyclophanes were evaluated for biological activities and the results showed that some of these compounds have low antibacterial or antifungal activities.

New substituted spiro[cycloalkyl-1,3'-indo]-2'(1'H)-one derivatives and their use as p38 mitogen-activated kinase inhibitors

This invention is directed to new inhibitors of the p38 mitogen-activated protein kinase having the general formula (I) to processes for their preparation; to pharmaceutical compositions comprising them; and to their use in therapy.