1312791-19-7Relevant articles and documents
A general copper-BINAP-catalyzed asymmetric propargylation of ketones with propargyl boronates
Fandrick, Keith R.,Fandrick, Daniel R.,Reeves, Jonathan T.,Gao, Joe,Ma, Shengli,Li, Wenjie,Lee, Heewon,Grinberg, Nelu,Lu, Bruce,Senanayake, Chris H.
supporting information; experimental part, p. 10332 - 10335 (2011/09/13)
An operationally simple copper-BINAP-catalyzed, highly enantioselective propargylation of ketones is presented. The methodology was developed as an enantioselective process for methyl ethyl ketone and shown to be applicable to a wide variety of prochiral