13130-30-8

Basic information

• Product Name: 3-(2-hydroxyphenyl)-6-nitro-2H-chromen-2-one
• Synonyms: 3-(2-hydroxyphenyl)-6-nitro-2H-chromen-2-one
• CAS NO: 13130-30-8
• Molecular Weight: 283.24
• Mol File: 13130-30-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(2-hydroxyphenyl)-6-nitro-2H-chromen-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-hydroxyphenyl)-6-nitro-2H-chromen-2-one(13130-30-8)
• EPA Substance Registry System: 3-(2-hydroxyphenyl)-6-nitro-2H-chromen-2-one(13130-30-8)

Safety Data

• Hazardous Substances Data: 13130-30-8(Hazardous Substances Data)

Upstream product

• 553-86-6 benzofuran-2(3H)-one 
• 97-51-8 5-Nitrosalicylaldehyde 

Relevant articles and documents

Copper-mediated synthesis of coumestans via C(sp2)-H functionalization: Protective group free route to coumestrol and 4′-O-methylcoumestrol

A simple and efficient two step synthesis of coumestans is described. The key reaction in the synthesis is the use of easily available Cu(OAc)2 for C[sbnd]H functionalization of 3-(2-hydroxyphenyl)coumarin to give coumestan ring system via formal oxidative cyclization. This approach provided a short protective group free route to naturally occurring coumestrol and 4′-O-methylcoumestrol.