1313484-36-4Relevant articles and documents
Synthesis of the B-seco limonoid core scaffold
Bruss, Hanna,Schuster, Hannah,Martinez, Remi,Kaiser, Markus,Antonchick, Andrey P.,Waldmann, Herbert
, p. 194 - 208 (2014/02/14)
Synthetic investigations towards the structurally complex and highly decorated framework of B-seco limonoid natural products by means of a [3,3]-sigmatropic rearrangement are described. Detailed model studies reveal, that an Ireland-Claisen rearrangement can be employed to construct the central C9-C10 bond thereby giving access to the B-seco limonoid scaffold. However, application of the developed strategy ended up failing in more complex and sterically demanding systems.