131352-46-0

Basic information

• Product Name: (R)-(+)-5,6-Dihydro-4H-thieno<2,3-b>thiopyran-4-ol 7,7-Dioxide
• CAS NO: 131352-46-0
• Molecular Weight: 204.271
• Mol File: 131352-46-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (R)-(+)-5,6-Dihydro-4H-thieno<2,3-b>thiopyran-4-ol 7,7-Dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-(+)-5,6-Dihydro-4H-thieno<2,3-b>thiopyran-4-ol 7,7-Dioxide(131352-46-0)
• EPA Substance Registry System: (R)-(+)-5,6-Dihydro-4H-thieno<2,3-b>thiopyran-4-ol 7,7-Dioxide(131352-46-0)

Safety Data

• Hazardous Substances Data: 131352-46-0(Hazardous Substances Data)

Upstream product

• 766-77-8 Dimethylphenylsilane 
• 131352-47-1 5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-one-7,7-dioxide 

Downstream Products

• 119271-78-2 (S)-(+)-5,6-Dihydro-4-<(2-methylpropyl)amino>-4H-thieno<2,3-b>thiopyran-2-sulfonamide 7,7-Dioxide Monohydrochloride (MK-0417) 
• 131352-49-3 Toluene-4-sulfonic acid (R)-7,7-dioxo-4,5,6,7-tetrahydro-7λ⁶-thieno[2,3-b]thiopyran-4-yl ester 

Relevant articles and documents

Enantioselective reduction of ketones and imines catalyzed by (CN-Box)ReV-oxo complexes

The development and application of chiral, non-racemic ReV-oxo complexes to the enantioselective reduction of prochiral ketones is described. In addition to the enantioselective reduction of prochiral ketones, we report the application of these complexes to 1) a tandem Meyer-Schuster rearrangement/reduction to access enantioenriched allylic alcohols and 2) the enantioselective reduction of imines.

A Practical Process for the Preparation of Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolooxazaborole-Borane. A Highly Enantioselective Stoichiometric and Catalytic Reducing Agent

A practical, large-scale process for the preparation of tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolooxazaborole-borane is reported.The title compound is a stable, free-flowing crystalline solid useful either stoichiometrically or catalytically for the enantioselective reduction of prochiral ketones.When used stoichiometrically to reduce acetophenone the enantioselectivity is >= 99.8 percent ee.