1313990-84-9

Basic information

• Product Name: ethyl 5-((2,6-dimethylphenyl)amino)-3,5-dioxopentanoate
• Synonyms: ethyl 5-((2,6-dimethylphenyl)amino)-3,5-dioxopentanoate
• CAS NO: 1313990-84-9
• Molecular Weight: 277.32
• Mol File: 1313990-84-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 5-((2,6-dimethylphenyl)amino)-3,5-dioxopentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 5-((2,6-dimethylphenyl)amino)-3,5-dioxopentanoate(1313990-84-9)
• EPA Substance Registry System: ethyl 5-((2,6-dimethylphenyl)amino)-3,5-dioxopentanoate(1313990-84-9)

Safety Data

• Hazardous Substances Data: 1313990-84-9(Hazardous Substances Data)

Upstream product

• 10521-08-1 pyran-2,4,6-trione 
• 542-05-2 acetonedicarboxylic acid 
• 5526-36-3 3-oxo-glutaric acid monoethyl ester 
• 87-62-7 2,6-dimethylaniline 

Relevant articles and documents

Ru-catalyzed asymmetric hydrogenation of 3-oxoglutaric acid derivatives via solvent-assisted pinpoint recognition of carbonyls in close chemical propinquity

Upon comparison of hydrogenation rates of various β-ketocarboxylic acid derivatives, β-ketoamides were found to be hydrogenated slightly faster than β-ketoesters in EtOH in the presence of [RuCl(benzene)(S)- SunPhos]Cl at 70 °C with 20 bar of hydrogen. In THF these differences were so sharpened that β-ketoamides were hydrogenated even faster than in EtOH while the esters were extremely slow. Based on these findings, a series of 3-oxoglutaric acid derived with ester and amide moieties on the two ends were hydrogenated to 3-hydroxyl products with high enantioselectivities.