13141-40-7

Basic information

• Product Name: Benzenemethanol, 2-(phenylethynyl)-
• CAS NO: 13141-40-7
• Molecular Formula: C15H12O
• Molecular Weight: 208.26
• Mol File: 13141-40-7.mol
• Article Data: 40

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 2-(phenylethynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 2-(phenylethynyl)-(13141-40-7)
• EPA Substance Registry System: Benzenemethanol, 2-(phenylethynyl)-(13141-40-7)

Safety Data

• Hazardous Substances Data: 13141-40-7(Hazardous Substances Data)

Usage

Physical Appearance

White to off-white powder

Common Uses

Production of pharmaceuticals
Production of dyes
Production of other organic compounds

Application as a Ligand

Used in coordination chemistry

Role in Organic Synthesis

Acts as a building block

Investigated Biological Activities

Serotonin reuptake inhibition
Antitumor properties

Versatility

Widely applicable across various industries.

Upstream product

• 59046-72-9 o-(phenylethynyl)benzaldehyde 
• 13146-23-1 copper(I) phenylacetylenide 
• 5159-41-1 2-iodobenzyl alcohol 
• 18982-54-2 o-bromobenzyl alcohol 
• 536-74-3 phenylacetylene 
• 26260-02-6 2-iodobenzaldehyde 
• 6630-33-7 ortho-bromobenzaldehyde 
• 226089-80-1 2-(2-benzenesulfonylmethyl-phenyl)-[1,3]dioxolane 
• 226089-86-7 2-(2-(phenylethynyl)phenyl)-1,3-dioxolane 
• 468751-38-4 ortho-(phenylsulfonylmethyl)benzaldehyde 
• 57341-98-7 4-(phenylethynyl)benzaldehyde 
• 30353-46-9 5-phenyl-2,4-pentadiyn-1-ol 
• 74-86-2 acetylene 

Downstream Products

• 467249-09-8 2-bromo-1-[2-(phenylethynyl)benzyl]-1H-indole-3-carboxaldehyde 
• 452094-04-1 C₆H₅CHCSn(C₄H₉)3C₆H₄(o-CH₂OH) 
• 1205555-55-0 4-iodo-3-phenyl-1H-isochromene 
• 1205555-72-1 (Z)-1-iodophenylmethylene-1,3-dihydroisobenzofuran 
• 1338726-11-6 (E)-4-(1-phenylethylidene)-3-isochromanone 
• 1620151-59-8 6a-phenyl-5,6a-dihydroisochromeno[3,4-b]chromene 
• 29539-10-4 3-phenyl-1H-isochromene 
• 1443309-11-2 C₂₂H₁₉N 
• 5033-67-0 2-(2-methylphenyl)-1-phenyl-1-ethanone 

Relevant articles and documents

Rapid, easy copper-free Sonogashira couplings using aryl iodides and activated aryl bromides

We present here an easy, rapid copper-free methodology for the Sonogashira coupling reaction. It works well for a range of aryl iodides and activated aryl bromides.

Accessing Polycyclic Heteroarenes Enabled by Copper-Catalyzed Aerobic Oxidative C–H/C–H [4 + 2] Annulation of 3-Arylindole Derivatives

Several polycyclic aromatic hydrocarbons are delivered at room temperature by copper-catalyzed aerobic oxidative C–H/C–H [4 + 2] annulation of alkyl-substituted 3-arylindole derivatives. Specifically, dual aryl C–H functionalization is furnished under mil

Alkyne Aminopalladation/Heck and Suzuki Cascades: An Approach to Tetrasubstituted Enamines

Alkyne aminopalladation reactions starting from tosylamides are reported. The emerging vinylic Pd species are converted either in an intramolecular Heck reaction with olefinic units or in an intermolecular Suzuki reaction by using boronic acids exhibiting broad functional group tolerance. Tetra(hetero)substituted tosylated enamines are obtained in a simple one-pot process.

Regio- and stereoselective intramolecular hydroalkoxylation of aromatic alkynols: an access to dihydroisobenzofurans under transition-metal-free conditions

An efficient, transition-metal-free method to synthesize dihydroisobenzofuran derivatives via intramolecular hydroalkoxylation of aromatic alkynols with the promotion of cesium carbonate has been developed. The reaction proceeds regioselectively with exclusive formation of 5-exo-dig product, and only Z-isomer of the new generated double bond is observed. This new protocol features with milder reaction conditions, more convenient operation and satisfactory selectivities.