1314119-12-4Relevant articles and documents
Discovery and hit-to-lead optimization of non-ATP competitive MK2 (MAPKAPK2) inhibitors
Huang, Xiaohua,Shipps, Gerald W.,Cheng, Cliff C.,Spacciapoli, Peter,Zhang, Xingmin,McCoy, Mark A.,Wyss, Daniel F.,Yang, Xianshu,Achab, Abdelghani,Soucy, Kyle,Montavon, Donna K.,Murphy, Denise M.,Whitehurst, Charles E.
scheme or table, p. 632 - 637 (2011/10/17)
A novel series of non-ATP-competitive MK2 inhibitors based on a furan-2-carboxyamide scaffold was discovered through high-throughput screening using the affinity selection-mass spectrometry-based Automated Ligand Identification System platform. Medicinal
