13142-79-5

Basic information

• Product Name: N-phenyl-N'-(2-hydroxylphenyl)urea
• Synonyms: N-phenyl-N'-(2-hydroxylphenyl)urea
• CAS NO: 13142-79-5
• Molecular Weight: 228.25
• Mol File: 13142-79-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-phenyl-N'-(2-hydroxylphenyl)urea(CAS DataBase Reference)
• NIST Chemistry Reference: N-phenyl-N'-(2-hydroxylphenyl)urea(13142-79-5)
• EPA Substance Registry System: N-phenyl-N'-(2-hydroxylphenyl)urea(13142-79-5)

Safety Data

• Hazardous Substances Data: 13142-79-5(Hazardous Substances Data)

Upstream product

• 60-29-7 diethyl ether 
• 103-71-9 phenyl isocyanate 
• 95-55-6 2-amino-phenol 
• 13142-82-0 N-(2-methoxyphenyl)-N'-phenyl-urea 
• 19226-36-9 3-phenyl-5H-1,4,2-dioxazol-5-one 

Downstream Products

• 130632-40-5 2-Dipropylamino-benzo[1,3,2]oxazaphosphole-3-carboxylic acid phenylamide 
• 130632-39-2 2-Diethylamino-benzo[1,3,2]oxazaphosphole-3-carboxylic acid phenylamide 
• 130632-38-1 2-Dimethylamino-benzo[1,3,2]oxazaphosphole-3-carboxylic acid phenylamide 
• 59-49-4 2-Benzoxazolinone 
• 130632-41-6 2-Dibutylamino-benzo[1,3,2]oxazaphosphole-3-carboxylic acid phenylamide 

Relevant articles and documents

Synthetic method and application of urea compound

The invention relates to a synthetic method of a urea compound, comprising the following steps: adding substituted oxazolone and sodium acetate into a methanol solution, and adding substituted amine under the stirring condition, reacting and carrying out column chromatography to obtain the urea compound. The defect that dangerous compounds need to be used during existing synthetic process is overcome, and a one-pot method is adopted to replace an existing reaction with low yield. The method of the invention has mild reaction condition, the operation is simple, raw materials are easily available, and the substrate can be converted into various other useful molecules. The compound has strong practicality, and can be applied to synthesis of the pesticide daimuron, dieresis long and the anti-cancer drug Sorafenib. The invention relates to a green and environmentally-friendly unsymmetrical urea compound synthesis method with simple process and low cost.