131456-84-3Relevant articles and documents
4-Amino-3-pyridinioquinolin-2(1H)-one Chlorides and 3,4-Diaminoquinolin-2(1H)-ones
Gewald, Karl,Schaefer, Harry,Bellmann, Peter,Mueller, Heike
, p. 1237 - 1241 (2007/10/02)
N-(Chloroacetyl)anthranilonitriles 1 react with the pyridines 2 to form the 4-amino-3-pyridinioquinolin-2(1H)-one chlorides 4, which are converted into the pyridoimidazoquinolin-6(5H)-ones 6 in the presence of sodium hydroxide or by cyclooxidation with bromine.Treatment of 4 with hydrazine hydrate yields the 3,4-diaminoquinolin-2(1H)-ones 9.Analogously to other diamines the substituted imidazoquinolinones 12, the pyrazinoquinolinones 13, 14, the 1,2,5-thiadiazoloquinolin-4-one 15a and the 1,2,5-selenadiazoloquinolin-4-one 15b are obtainable from 9a.With chloroacetyl chloride 9a provides the oxazinoquinolin-2-one 11.