1314602-96-4

Basic information

• Product Name: C₂₂H₁₇BrN₄O₄S
• Synonyms: C₂₂H₁₇BrN₄O₄S
• CAS NO: 1314602-96-4
• Molecular Weight: 513.371
• Mol File: 1314602-96-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₂H₁₇BrN₄O₄S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₂H₁₇BrN₄O₄S(1314602-96-4)
• EPA Substance Registry System: C₂₂H₁₇BrN₄O₄S(1314602-96-4)

Safety Data

• Hazardous Substances Data: 1314602-96-4(Hazardous Substances Data)

Upstream product

• 857589-28-7 2-benzamido-5-bromobenzoic acid 
• 3989-50-2 4-acetamidobenzenesulfonylhydrazine 

Downstream Products

• 1314603-05-8 4-amino-N-(6-bromo-4-oxo-2-phenylquinazolin-3(4H)-yl)benzenesulfonamide 

Relevant articles and documents

A convergent microwave assisted synthesis of 4-amino-N-(4-oxo-2- substituted-4H-quinazolin-3-yl)benzenesulfonamide derivatives

An optimization of Grimmel's method under microwave irradiation is reported here for the first time to synthesize 4-amino-N-(4-oxo-2-substituted-4H- quinazolin-3-yl)benzenesulfonamide derivatives. The method was successfully applied for the synthesis of 2-alkyl and 2-aryl substituted derivatives. However, unexpected results were obtained when the same protocol was applied for 2-styryl-substituted quinazolinones. 2-Styrylquinazolinone derivatives were then synthesized via benzoxazinones under microwave irradiation. Subsequently, the effect of various bases (e.g. Et3N, NMM, DMAP, DIPEA) on the efficiency of cyclization to quinazolinone was investigated. The use of microwave irradiation allows significant rate enhancements and better yields compared to conventional conditions. ARKAT-USA, Inc.