1314876-73-7

Basic information

• Product Name: α-D-mannopyranosyl-(1->3)-2-amino-1,2-deoxy-1-(2-triphenylmethylthioeth-2-ylamino)-D-glucitol
• CAS NO: 1314876-73-7
• Molecular Weight: 644.786
• Mol File: 1314876-73-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: α-D-mannopyranosyl-(1->3)-2-amino-1,2-deoxy-1-(2-triphenylmethylthioeth-2-ylamino)-D-glucitol(CAS DataBase Reference)
• NIST Chemistry Reference: α-D-mannopyranosyl-(1->3)-2-amino-1,2-deoxy-1-(2-triphenylmethylthioeth-2-ylamino)-D-glucitol(1314876-73-7)
• EPA Substance Registry System: α-D-mannopyranosyl-(1->3)-2-amino-1,2-deoxy-1-(2-triphenylmethylthioeth-2-ylamino)-D-glucitol(1314876-73-7)

Safety Data

• Hazardous Substances Data: 1314876-73-7(Hazardous Substances Data)

Upstream product

• 489-52-1 α-D-mannopyranosyl-(1->3)-2-acetamido-2-deoxy-D-glucopyranose 
• 1095-85-8 2-amino tritylthio ethane 
• 54400-75-8 allyl 2-acetamido-2-deoxy-β-D-glucopyranoside 
• 1314876-69-1 allyl 2-acetamido-4,6-di-O-acetyl-2-deoxy-3-O-levulinoyl-β-D-glucopyranoside 
• 1314876-68-0 allyl 2-acetamido-2-deoxy-3-O-levulinoyl-4,6-O-p-methoxybenzylidene-β-D-glucopyranoside 
• 1314876-71-5 allyl 2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyl-(1->3)-2-acetamido-4,6-di-O-acetyl-2-deoxy-β-D-gluco-pyranoside 
• 1314876-70-4 allyl 2-acetamido-4,6-di-O-acetyl-2-deoxy-β-D-glucopyranoside 

Relevant articles and documents

Synthesis of a mannose-bearing disaccharide with a thiol spacer at the reducing end

The synthesis of a mannose-bearing disaccharide containing a thiol spacer at the reducing end was carried out to provide a tethered sugar suitable for attaching to gold nanoparticles. An array of such sugars is designed to mimic carbohydrates involved in cell-surface interactions. The molecule was constructed via Schmidt glycosylation of an appropriately protected glycosyl donor and an acceptor, followed by removal of protective groups and reductive amination to introduce a protected thiol spacer at the reducing end of the glycan. A new finding that the anomeric reductive amination is capable of concomitantly removing a neighboring N-acetyl group was also observed. Subsequent removal of the thiol protective group and purification of the product gave the target disaccharide in a satisfactory yield.