131501-50-3

Basic information

• Product Name: uridine 5'-(2-acetamido-2,3-di-deoxy-α-D-glucopyranosyl diphosphate) disodium salt
• Synonyms: uridine 5'-(2-acetamido-2,3-di-deoxy-α-D-glucopyranosyl diphosphate) disodium salt
• CAS NO: 131501-50-3
• Molecular Weight: 635.323
• Mol File: 131501-50-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: uridine 5'-(2-acetamido-2,3-di-deoxy-α-D-glucopyranosyl diphosphate) disodium salt(CAS DataBase Reference)
• NIST Chemistry Reference: uridine 5'-(2-acetamido-2,3-di-deoxy-α-D-glucopyranosyl diphosphate) disodium salt(131501-50-3)
• EPA Substance Registry System: uridine 5'-(2-acetamido-2,3-di-deoxy-α-D-glucopyranosyl diphosphate) disodium salt(131501-50-3)

Safety Data

• Hazardous Substances Data: 131501-50-3(Hazardous Substances Data)

Upstream product

• 131473-50-2 C₈H₁₄NO₈P^(2-)*2Na⁽¹⁺⁾ 
• 27908-36-7 uridine 5'-monophosphate morpholidate 

Relevant articles and documents

Combined chemical-enzymic synthesis of deoxygenated oligosaccharide analogs: transfer of deoxygenated D-GlcpNAc residues from their UDP-GlcpNAc derivatives using N-acetylglucosaminyltransferase I

The 3"-,4"-, and 6"-deoxy analogs of UDP-GlcpNAc have been synthesized chemically and found to act as donor-substrates for N-acetylglucosaminyltransferase-I (GnT-I) from human milk.Incubation of UDP-GlcpNAc and these deoxy analogs with GnT-I in the presence of α-D-Manp-(1->3)-6)>-β-D-Manp-O(CH2)8COOMe gave β-D-GlcpNAc-(1->2)-α-D-Manp-(1->3)-6)>-β-D-Manp-O(CH2)8COOMe(6), and the deoxy analogs 12-14 where HO-3, HO-4, and HO-6, respectively, of the β-D-GlcNAc residue were replaced by hydrogen.The tetrasaccharide glycosides 6 and 12-14 were characterized by 1H-n.m.r. spectroscopy and evaluated as acceptors for GnT-II, the next enzyme in the pathway of biosynthesis of Asn-linked oligosaccharides.Deoxygenation of the 3-position of the β-D-GlcNAc residue of 6 completely abolished its acceptor activity, whereas removal of HO-4 or HO-6 caused only modest decreases in activity.