131506-23-5Relevant articles and documents
N-substituted amides
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, (2008/06/13)
N-substituted amides which inhibit hydrolysis of elastin, are described, which compounds are tri-and di- fluoromethyl ketone amide and non-naturally occurring n-substituted amino acids derivatives.
Inhibition of human leukocyte elastase by N-substituted peptides containing α,α-difluorostatone residues at P1
Skiles,Miao,Sorcek,Jacober,Mui,Chow,Weldon,Possanza,Skoog,Keirns,Letts,Rosenthal
, p. 4795 - 4808 (2007/10/02)
A series of tripeptides which contain α,α-difluorostatone residues at P1-P1' and span the S3-S1' subsites have been shown to be potent inhibitors of human leukocyte elastase (HLE). The tripeptides described cont
