13152-96-0

Basic information

• Product Name: Methanone, (2,5-dimethylphenyl)(4-methylphenyl)-
• CAS NO: 13152-96-0
• Molecular Formula: C16H16O
• Molecular Weight: 224.302
• Mol File: 13152-96-0.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: Methanone, (2,5-dimethylphenyl)(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (2,5-dimethylphenyl)(4-methylphenyl)-(13152-96-0)
• EPA Substance Registry System: Methanone, (2,5-dimethylphenyl)(4-methylphenyl)-(13152-96-0)

Safety Data

• Hazardous Substances Data: 13152-96-0(Hazardous Substances Data)

Upstream product

• 106-42-3 para-xylene 
• 201230-82-2 carbon monoxide 
• 624-31-7 4-tolyl iodide 
• 19226-36-9 3-phenyl-5H-1,4,2-dioxazol-5-one 
• 13756-42-8 tert-butyl 4-methylbenzoate 
• 104-82-5 4-Methylbenzyl chloride 
• 20809-75-0 Methyl-2-(2,5-dimethyl-phenyl)-2-hydroxy-3-oxo-succinat 
• 20809-77-2 Methyl-2,2-(2,5,4'-trimethyl-diphenyl)-3-oxo-succinat 
• 99-94-5 p-Toluic acid 
• 22328-43-4 2,5-dimethylbenzoyl chloride 
• 108-88-3 toluene 
• 721-45-9 1,4-dimethyl-2-(4-methylbenzyl)benzene 
• 874-60-2 4-methyl-benzoyl chloride 
• 95-72-7 2-chloro-1,4-dimethyl-benzene 

Downstream Products

• 186971-82-4 9,10-dihydro-anthracene-2,6-dicarboxylic acid 
• 138308-89-1 2,6-anthracene dicarboxylic acid 
• 613-26-3 2,6-dimethylanthracene 
• 146780-99-6 2,6-dimethyl-anthrone 
• 721-45-9 1,4-dimethyl-2-(4-methylbenzyl)benzene 
• 53039-57-9 (4-methoxyphenyl)-(2-methoxy-5-methylphenyl)methane 

Relevant articles and documents

A general approach to intermolecular carbonylation of arene C-H bonds to ketones through catalytic aroyl triflate formation

The development of metal-catalysed methods to functionalize inert C-H bonds has become a dominant research theme in the past decade as an approach to efficient synthesis. However, the incorporation of carbon monoxide into such reactions to form valuable ketones has to date proved a challenge, despite its potential as a straightforward and green alternative to Friedel-Crafts reactions. Here we describe a new approach to palladium-catalysed C-H bond functionalization in which carbon monoxide is used to drive the generation of high-energy electrophiles. This offers a method to couple the useful features of metal-catalysed C-H functionalization (stable and available reagents) and electrophilic acylations (broad scope and selectivity), and synthesize ketones simply from aryl iodides, CO and arenes. Notably, the reaction proceeds in an intermolecular fashion, without directing groups and at very low palladium-catalyst loadings. Mechanistic studies show that the reaction proceeds through the catalytic build-up of potent aroyl triflate electrophiles.

Co(III)-Catalyzed Synthesis of Quinazolines via C-H Activation of N-Sulfinylimines and Benzimidates

C-H activation of arenes has been established as an important strategy for heterocycle synthesis via annulations between arenes and unsaturated coupling partners. However, nitriles failed to act as such a coupling partner. Dioxazolones have been employed as a synthon of nitriles, and subsequent coupling with arenes such as N-sulfinylimines and benzimidates bearing a functionalizable directing group provided facile access to two classes of quinazolines under Co(III)-catalysis.

Design, synthesis and characterization of self-assembled As 2L3 and Sb2L3 cryptands

The syntheses and X-ray crystal structures of six new self-assembled supramolecular As and Sb-containing cryptands are described. Analysis in the context of previously reported As2L3 and Sb 2L3 cryptands reveals that small differences in ligand geometries result in significant differences in the helicity of the complexes and the stereochemistry of the metal coordination within the assembled complexes. Additionally, a new synthetic route is described which involves exposure of reactants to vacuum to help facilitate self-assembly.