131549-85-4 Usage
Description
4-nitrososulfamethoxazole is a sulfonamide compound characterized by the presence of a 4-nitrosophenyl group attached to the sulfur atom and a 1,2-oxazol-3-yl group attached to the nitrogen atom. It is a yellow solid and is known for its pharmaceutical applications.
Uses
Used in Pharmaceutical Industry:
4-nitrososulfamethoxazole is used as an active pharmaceutical ingredient for its potential therapeutic effects. The compound's unique structure allows it to interact with various biological targets, making it a promising candidate for the development of new drugs to treat various diseases.
Used in Research and Development:
In the field of research and development, 4-nitrososulfamethoxazole serves as a valuable compound for studying the structure-activity relationships of sulfonamide-based drugs. Its chemical properties and reactivity can provide insights into the design and synthesis of novel sulfonamide derivatives with improved pharmacological properties.
Used in Drug Synthesis:
4-nitrososulfamethoxazole can be utilized as a key intermediate in the synthesis of other sulfonamide-based drugs. Its unique functional groups can be further modified or reacted with other molecules to create new drug candidates with enhanced efficacy, selectivity, and safety profiles.
Used in Quality Control and Standardization:
As a reference compound, 4-nitrososulfamethoxazole can be employed in the quality control and standardization of sulfonamide drugs. It can be used to establish purity standards, validate analytical methods, and ensure the consistency and reliability of pharmaceutical products containing sulfonamide moieties.
Check Digit Verification of cas no
The CAS Registry Mumber 131549-85-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,5,4 and 9 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 131549-85:
(8*1)+(7*3)+(6*1)+(5*5)+(4*4)+(3*9)+(2*8)+(1*5)=124
124 % 10 = 4
So 131549-85-4 is a valid CAS Registry Number.
InChI:InChI=1/C10H9N3O4S/c1-7-6-10(12-17-7)13-18(15,16)9-4-2-8(11-14)3-5-9/h2-6H,1H3,(H,12,13)
131549-85-4Relevant articles and documents
Insights into the electrochemical degradation of sulfamethoxazole and its metabolite by Ti/SnO2-Sb/Er-PbO2 anode
Wang, Yanping,Zhou, Chengzhi,Wu, Jinhua,Niu, Junfeng
supporting information, p. 2673 - 2677 (2020/06/01)
Electrochemical degradation of sulfamethoxazole (SMX) and its metabolite acetyl-sulfamethoxazole (Ac-SMX) by Ti/SnO2-Sb/Er-PbO2 were investigated. Results indicated that the electrochemical degradation of SMX and Ac-SMX followed pseu
Synthesis and reactions of nitroso sulphamethoxazole with biological nucleophiles: Implications for immune mediated toxicity
Naisbitt, Dean J.,Neill, Paul M.,Pirmohamed, Munir,Park, B. Kevin
, p. 1511 - 1516 (2007/10/03)
Sulphamethoxazole hydroxylamine (SMX-NHOH) and nitroso sulphamethoxazole (SMX-NO) were prepared by a modified literature procedure. SMX-NO produced a complex set of unstable intermediates with sulphur nucleophiles, but did not react with amino containing compounds. No reactions were observed between sulphamethoxazole (SMX) / SMX-NHOH and the nucleophiles used in this study. Thus antigens formed from N-oxidation of SMX are likely to be unstable in vivo.