131589-03-2

Basic information

• Product Name: 3-Cyclobutene-1,2-dione, 3-ethoxy-4-[[(1S,2R)-2-hydroxy-1-methyl-2-phenylethyl]methylamino]-
• CAS NO: 131589-03-2
• Molecular Formula: C16H19NO4
• Molecular Weight: 289.331
• Mol File: 131589-03-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Cyclobutene-1,2-dione, 3-ethoxy-4-[[(1S,2R)-2-hydroxy-1-methyl-2-phenylethyl]methylamino]-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Cyclobutene-1,2-dione, 3-ethoxy-4-[[(1S,2R)-2-hydroxy-1-methyl-2-phenylethyl]methylamino]-(131589-03-2)
• EPA Substance Registry System: 3-Cyclobutene-1,2-dione, 3-ethoxy-4-[[(1S,2R)-2-hydroxy-1-methyl-2-phenylethyl]methylamino]-(131589-03-2)

Safety Data

• Hazardous Substances Data: 131589-03-2(Hazardous Substances Data)

Upstream product

• 299-42-3 ephedrine 
• 5231-87-8 3,4-diethoxy-3-cyclobuten-1,2-dione 

Relevant articles and documents

Anticancer Agents, 15. Squaric Acid Diethyl Ester: A New Coupling Reagent for the Formation of Drug Biopolymer Conjugates. Synthesis of Squaric Acid Ester Amides and Diamides

Reaction of squaric acid diethyl ester (1) with a slight excess of a primary or secondary amine 2 in ethanol, dichloromethane or aqueous buffer (pH 7) at 20 deg C for 0.3 - 12 h gives the squaric acid amide esters 3 in mostly excellent yields.Treatment of