1316189-13-5

Basic information

• Product Name: MPEG8-NHS
• Synonyms: MPEG8-NHS;m-PEG9-NHS ester;mPEG8-CH2CH2COONHS Ester
• CAS NO: 1316189-13-5
• Molecular Formula: C24H43NO13
• Molecular Weight: 553.59712
• Product Categories: mPEG
• Mol File: 1316189-13-5.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 598.3±60.0 °C(Predicted)
• Appearance: /
• Density: 1.20±0.1 g/cm3(Predicted)
• Solubility: Soluble in DMSO, DCM, DMF
• CAS DataBase Reference: MPEG8-NHS(CAS DataBase Reference)
• NIST Chemistry Reference: MPEG8-NHS(1316189-13-5)
• EPA Substance Registry System: MPEG8-NHS(1316189-13-5)

Safety Data

• Hazardous Substances Data: 1316189-13-5(Hazardous Substances Data)

Usage

Description

MPEG8-NHS, also known as m-PEG9-NHS ester, is a PEG (polyethylene glycol) linker containing an NHS (N-hydroxysuccinimide) ester. This NHS ester allows for the labeling of primary amines (-NH2) found in proteins, amine-modified oligonucleotides, and other amine-containing molecules. The hydrophilic PEG spacer enhances solubility in aqueous media, making MPEG8-NHS a versatile tool in various applications.

Uses

Used in Bioconjugation:
MPEG8-NHS is used as a bioconjugation agent for attaching proteins, peptides, or other amine-containing molecules to various surfaces or supports. The NHS ester reacts with primary amines to form stable amide bonds, facilitating the covalent attachment of biomolecules.
Used in Drug Delivery Systems:
In the pharmaceutical industry, MPEG8-NHS is used as a component in drug delivery systems. The PEG spacer improves the solubility and stability of drug molecules, while the NHS ester allows for the attachment of therapeutic agents to carriers or nanoparticles.
Used in Diagnostics and Imaging:
MPEG8-NHS is used as a labeling agent in diagnostic and imaging applications. The NHS ester can be used to attach imaging agents or contrast molecules to biomolecules, enabling their detection and visualization in various imaging modalities.
Used in Research and Development:
In research settings, MPEG8-NHS is used as a tool for the modification and functionalization of amine-containing molecules. This allows scientists to study the properties and interactions of these molecules, as well as to develop new materials and applications.