131619-68-6

Basic information

• Product Name: N-<4-<<(4-amino-1-methyl-2,2-dioxopyrazino<2,3-c>-1,2,6-thiadiazin-7-yl)methyl>amino>benzoyl>-L-glutamic acid
• CAS NO: 131619-68-6
• Molecular Weight: 491.484
• Mol File: 131619-68-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-<4-<<(4-amino-1-methyl-2,2-dioxopyrazino<2,3-c>-1,2,6-thiadiazin-7-yl)methyl>amino>benzoyl>-L-glutamic acid(CAS DataBase Reference)
• NIST Chemistry Reference: N-<4-<<(4-amino-1-methyl-2,2-dioxopyrazino<2,3-c>-1,2,6-thiadiazin-7-yl)methyl>amino>benzoyl>-L-glutamic acid(131619-68-6)
• EPA Substance Registry System: N-<4-<<(4-amino-1-methyl-2,2-dioxopyrazino<2,3-c>-1,2,6-thiadiazin-7-yl)methyl>amino>benzoyl>-L-glutamic acid(131619-68-6)

Safety Data

• Hazardous Substances Data: 131619-68-6(Hazardous Substances Data)

Upstream product

• 131619-62-0 4-amino-1,7-dimethylpyrazino<2,3-c>-1,2,6-thiadiazine 2,2-dioxide 
• 131619-60-8 4-amino-7-methyl-1H-pyrazino<2,3-c>-<1,2,6>thiadiazine 2,2-dioxide 
• 4271-30-1 N-(4-aminobenzoyl)-L-glutamic acid 
• 131619-64-2 7-Bromomethyl-1-methyl-2,2-dioxo-1,2-dihydro-2λ⁶-pyrazino[2,3-c][1,2,6]thiadiazin-4-ylamine 

Relevant articles and documents

Pyrazino-1,2,6-thiadiazine 2,2-Dioxides. Synthesis of SO2 Analogues of Folic Acid Antagonists

The synthesis of novel analogues of folic acid (FA) antagonists derived from the pyrazino-1,2,6-thiadiazine 2,2-dioxide system incorporating the glutamic acid side chain at the 7-position is describrd.No significant DHFR inhibition of cytotoxic act