131652-00-1Relevant articles and documents
Synthesis of Pyrimidinone and 5-unsubstituted 4, 6-diarylpyrimidine-2(1H)-ones by Using Nano Magnetic Catalyst under Solvent Free Condition
Amoozadeh, Ali,Azhari, Saeede,Kolvari, Eskandar,Otokesh, Somayeh
, p. 968 - 973 (2015)
Nano magnetic-supported sulfonic acid is found to be a powerful and reusable heterogeneous catalyst for the efficient synthesis of pyrimidinones. In this study we use various ketones such as acetophenone and cyclopentanone instead of β-keto ester in one-p
Application of O-sulfonic acid poly(4-vinylpyrrolidonium) chloride as an efficient polymer-supported catalyst in the rapid synthesis of 2H-indazolo[2,1-b]phthalazine-triones and Biginelli-like products
Dalil Heirati, Seyedeh Zahra,Shirini, Farhad,Fallah Shojaei, Abdollah
, p. 3217 - 3225 (2020/07/02)
In this work, a series of 2H-indazolo[2,1-b]phthalazine-triones and Biginelli-like products were efficiently synthesized for the first time using O-Sulfonic acid poly(4-vinylpyrrolidonium) chloride ([PVP-SO3H]Cl) as an eco-friendly polymer-supp
Bronsted acidic ionic liquid [C3SO3HDoim]HSO4 catalyzed one-pot three-component Biginelli-type reaction: An efficient and solvent-free synthesis of pyrimidinone derivatives and its mechanistic study
Zhou, Zhi-Lei,Wang, Peng-Cheng,Lu, Ming
, p. 226 - 230 (2018/03/27)
A series of Bronsted acidic ionic liquids (ILs) were prepared and used for Biginelli-type condensation reaction among aromatic aldehydes, urea or thiourea and cyclopentanone. Through this reaction, the synthesis of various pyrimidinones could be achieved. Of interest, it was found that the reaction was efficiently catalyzed by a novel, eco-friendly functionalized IL [C3SO3HDoim]HSO4, which could be reused for at least 7 times without significantly loss of catalytic activity. The reaction proceeded efficiently at 80 °C to afford the desired products in good yield (up to 96%). In addition, a possible mechanism that accounted for the IL [C3SO3HDoim]HSO4-catalyzed reaction was proposed.