131699-18-8

Basic information

• Product Name: methyl 5-(3,4-dimethoxyphenyl)pentanoate
• Synonyms: methyl 5-(3,4-dimethoxyphenyl)pentanoate
• CAS NO: 131699-18-8
• Molecular Weight: 252.31
• Mol File: 131699-18-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl 5-(3,4-dimethoxyphenyl)pentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 5-(3,4-dimethoxyphenyl)pentanoate(131699-18-8)
• EPA Substance Registry System: methyl 5-(3,4-dimethoxyphenyl)pentanoate(131699-18-8)

Safety Data

• Hazardous Substances Data: 131699-18-8(Hazardous Substances Data)

Upstream product

• 91-16-7 1,2-dimethoxybenzene 
• 131699-22-4 5-(3,4-dimethoxy-phenyl)-5-oxo-pentanoic acid methyl ester 
• 108-55-4 glutaric anhydride, 
• 4378-55-6 5-(3,4-dimethoxy-phenyl)-5-oxo-pentanoic acid 
• 69731-27-7 (E)-1-bromo-2-(3,4-dimethoxyphenyl)ethene 
• 292638-85-8 acrylic acid methyl ester 

Downstream Products

• 1145-15-9 5-(3,4-dimethoxyphenyl)pentanoic acid 

Relevant articles and documents

An investigation into the one-pot Heck olefination-hydrogenation reaction

Herein is described an operationally simple process concerning the observation that, following either inter-, or intramolecular Heck olefination, stirring of the so formed substituted alkenyl product under an atmosphere of hydrogen efficiently effects alkene hydrogenation. Overall this two-operation, one-pot "reductive Heck" sequence is notable since direct reductive Heck processes, using additives such as formate salts, are restricted to a limited range of substrates. In total 25 examples are reported (yields ranging from 0 to 95%), which were selected in order to probe the scope and limitations of this method. Finally, the utility of this sequence was demonstrated in a short synthesis of the calcimimetic agent, cinacalcet.