131738-74-4Relevant articles and documents
Diastereoselective Conjugate Addition Approach to Picenadol and Oxygenated Analogues
Martinelli, Michael J.,Peterson, Barry C.,Hutchison, Darrell R.
, p. 2087 - 2098 (2007/10/02)
Horner-Emmons-Wadsworth reaction with 1,3-dimethyl-4-piperidone in water afforded an exocyclic enone, with minimal deconjugation of the double bond.Copper catalyzed conjugate addition with an aryl Grignard reagent then afforded an adduct with high stereoc