131802-60-3 Usage
Description
7-Benzyloxyquinoline is a chemical compound that serves as a marker substrate for cytochrome P450 3A4, an enzyme involved in the metabolism of various drugs and other substances in the body. It is characterized by its benzyloxy group attached to a quinoline core, which contributes to its unique properties and applications.
Uses
Used in Pharmaceutical Industry:
7-Benzyloxyquinoline is used as a screening agent for cytochrome P450 3A4 inhibition. It is employed to predict the potential for drug-drug interactions by identifying new chemical entities that may inhibit the activity of CYP3A4, a key enzyme in drug metabolism. This high-throughput screening method helps in the early stages of drug development to assess the safety and efficacy of new compounds, ensuring that potential drug interactions are identified and addressed.
Biochem/physiol Actions
Fluorogenic substrate for CYP3A4.
Check Digit Verification of cas no
The CAS Registry Mumber 131802-60-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,1,8,0 and 2 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 131802-60:
(8*1)+(7*3)+(6*1)+(5*8)+(4*0)+(3*2)+(2*6)+(1*0)=93
93 % 10 = 3
So 131802-60-3 is a valid CAS Registry Number.
InChI:InChI=1/C16H13NO/c1-2-5-13(6-3-1)12-18-15-9-8-14-7-4-10-17-16(14)11-15/h1-11H,12H2
