13181-14-1

Basic information

• Product Name: Ethanone, 1-phenyl-, O-(2,4-dinitrophenyl)oxime
• CAS NO: 13181-14-1
• Molecular Formula: C14H11N3O5
• Molecular Weight: 301.258
• Mol File: 13181-14-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Ethanone, 1-phenyl-, O-(2,4-dinitrophenyl)oxime(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-phenyl-, O-(2,4-dinitrophenyl)oxime(13181-14-1)
• EPA Substance Registry System: Ethanone, 1-phenyl-, O-(2,4-dinitrophenyl)oxime(13181-14-1)

Safety Data

• Hazardous Substances Data: 13181-14-1(Hazardous Substances Data)

Upstream product

• 98-86-2 acetophenone 
• 17508-17-7 O-(2,4-dinitrophenyl)hydroxylamine 

Downstream Products

• 14552-00-2 1-(2,4-dinitrophenyl)pyrrolidine 
• 41398-67-8 2-phenylethynylanisole 
• 13059-86-4 2,4-dinitro-N-butylaniline 
• 613-91-2 acetophenone oxime 
• 21552-98-7 N-(2,4-dinitrophenyl)pentylamine 
• 2044-88-4 N-methyl-2,4-dinitroaniline 
• 3846-50-2 2,4-dinitro-N-ethylaniline 
• 13059-84-2 2,4-dinitro-N-propylaniline 
• 52790-65-5 N-(2,4-dinitrophenyl)hexylamine 
• 839-93-0 1-(2,4-dinitrophenyl)piperidine 

Relevant articles and documents

Ligand-Promoted Alkynylation of Aryl Ketones: A Practical Tool for Structural Diversity in Drugs and Natural Products

Conversion of the numerous aryl ketones into aryl electrophiles via Ar-C(O) cleavage remains a challenging yet highly desirable transformation in Sonogashira-type coupling. Herein, we report a palladium-catalyzed ligand-promoted alkynylation of unstrained aryl ketones. The protocol allows the alkynylation to be carried out in a one-pot procedure with broad functional-group tolerance and substrate scope. The potential applications of this protocol in drug discovery and chemical biology are further demonstrated by late-stage diversification of a number of pharmaceuticals and natural products. More importantly, two different biologically important fragments derived from a pharmaceutical and natural product could be connected by the consecutive alkynylation of ketones. Distinct from aryl halides in conventional Sonogashira reactions, the protocol provides a practical tool for the 1,2-bifunctionalization of aryl ketone by merging ketone-directed ortho-C-H activation with ligand-promoted ipso-Ar-C(O) alkynylation.

Oxime ethers and pesticidal preparations containing them

New oxime ethers and pesticidal and herbicidal preparations containing them are disclosed. The oxime ethers correspond to the formula SPC1 Wherein R1 is a hydrogen atom or a lower alkyl radical; R2 is an aliphatic, cycloaliphatic, araliphatic, aromatic or heterocyclic radical; or wherein R1 and R2 form part of a saturated or unsaturated carbocycle or a 5-, 6- or 7-membered heterocycle; R3 is nitro, trifluoromethyl, formyl, lower carbalkoxy, sulfamyl or mono- or di-lower alkyl fulfamyl radical; R4- and R5 each is a hydrogen or halogen atom, an amino, mono- or di-lower alkyl amino, lower alkoxy, cycloalkoxy, lower alkylthio, nitro, lower carbalkoxy, arylthio, lower aralkylthio or lower alkyl group, or 5-, 6- or 7-membered heterocycle.