1318133-32-2

Basic information

• Product Name: 4-AMino-7-broMo-thieno[3,...
• Synonyms: 4-AMino-7-broMo-thieno[3,...;4-AMino-7-broMo-thieno[3,2-d]pyriMidine;7-broMothieno[3,2-d]pyriMidin-4-aMine
• CAS NO: 1318133-32-2
• Molecular Formula: C₆H₄BrN₃S
• Molecular Weight: 230.08506
• Mol File: 1318133-32-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 403.5±40.0 °C(Predicted)
• Appearance: /
• Density: 1.950±0.06 g/cm3(Predicted)
• PKA: 4.07±0.40(Predicted)
• CAS DataBase Reference: 4-AMino-7-broMo-thieno[3,...(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMino-7-broMo-thieno[3,...(1318133-32-2)
• EPA Substance Registry System: 4-AMino-7-broMo-thieno[3,...(1318133-32-2)

Safety Data

• Hazardous Substances Data: 1318133-32-2(Hazardous Substances Data)

Usage

General Description

The chemicals "4-AMino-7-broMo-thieno[3,..." belong to a larger category of compounds known as thienopyrimidinones. These compounds, including 4-amino-7-bromo variants, have been extensively studied for their pharmacological properties. Although the exact pharmacological profile can vary depending on the specific structure of the compound, many thienopyrimidinones exhibit potential anti-cancer, anti-inflammatory, and anti-microbial activities. Interestingly, some of these compounds also show promise as kinase inhibitors, which are increasingly used in targeted cancer therapies. As a result, the "4-AMino-7-broMo-thieno[3,..." chemicals and related compounds have attracted significant interest in the field of medicinal chemistry.

Upstream product

• 16234-10-9 3H-thieno[3,2-d]pyrimidin-4-one 
• 31169-27-4 7-bromo-4-chlorothieno[3,2-d]pyrimidine 
• 31169-25-2 7-bromothieno[3,2-d]pyrimidine-4(3H)-one 
• 22288-78-4 Methyl 3-aminothiophene-2-carboxylate 

Downstream Products

• 1318126-97-4 7-(4-bromo-3,5-dimethoxystyryl)thieno[3,2-d]pyrimidine-4-amine 
• 1318127-08-0 (E)-ethyl-3-(2-(4-aminothieno[3,2-d]pyrimidine-7-yl)vinyl)-4-methyl benzoate 
• 1318242-75-9 (E)-3-(2-(4-aminothieno[3,2-d]pyrimidine-7-yl)vinyl)-4-methylbenzoic acid 
• 1318241-43-8 (E)-3-(2-(4-aminothieno[3,2-d]pyrimidine-7-yl)vinyl)-4-methyl-N-(3-(trifluoromethyl)phenyl)benzamide 
• 1446111-75-6 4-amino-N-(4-((4-chlorophenyl)amino)-7-methylquinazolin-8-yl)thieno[3,2-d]pyrimidine-7-carboxamide 
• 1446111-86-9 4-amino-N-(6-methyl-1-phenoxyisoquinolin-5-yl)thieno[3,2-d]pyrimidine-7-carboxamide 
• 1446112-11-3 4-amino-N-(1-((4-chloro-3-((dimethylamino)methyl)phenyl)amino)-6-methylisoquinolin-5-yl)thieno[3,2-d]pyrimidine-7-carboxamide 
• 1446112-26-0 4-amino-N-(6-methyl-1-((3-(methylsulfonamido)phenyl)amino)isoquinolin-5-yl)thieno[3,2-d]pyrimidine-7-carboxamide 
• 1446112-28-2 tert-butyl 4-(5-((5-(4-aminothieno[3,2-d]pyrimidine-7-carboxamido)-6-methylisoquinolin-1-yl)amino)-2-chlorobenzyl)piperazine-1-carboxylate 
• 1446112-30-6 4-amino-N-(1-((4-chloro-3-(piperazin-1-ylmethyl)phenyl)amino)-6-methylisoquinolin-5-yl)thieno[3,2-d]pyrimidine-7-carboxamide hydrochloride 
• 1318242-98-6 4-amino-thieno[3,2-d]pyrimidine-7-carboxylic acid 
• 1446111-26-7 4-amino-N-(1-((4-chlorophenyl)amino)-6-methylisoquinolin-5-yl)thieno[3,2-d]pyrimidine-7-carboxamide 

Relevant articles and documents

FUSED PYRIMIDINE DERIVATIVES HAVING INHIBITORY ACTIVITY ON FMS KINASES

Disclosed are a fused pyrimidine derivative of formula (I), and a pharmaceutically acceptable salt, stereoisomer, hydrate and solvate thereof, which have an excellent inhibitory activity on FMS kinases, and a pharmaceutical composition comprising the same is effective in preventing or treating diseases caused by abnormal activation of FMS kinases such as immunologic diseases, metabolic diseases, inflammatory diseases, cancers and tumors.

THIENO[3,2-d]PYRIMIDINE DERIVATIVES HAVING INHIBITORY ACTIVITY ON PROTEIN KINASES

The present invention relates to a thieno[3,2-d]pyrimidine derivative of formula (I), or a pharmaceutically acceptable salt, hydrate or solvate thereof, which has an excellent inhibitory activity on protein kinases, and a pharmaceutical composition comprising the same is effective in preventing or treating abnormal cell growth diseases.

BICYCLIC HETEROARYL DERIVATIVES HAVING INHIBITORY ACTIVITY FOR PROTEIN KINASE

The present invention relates to a novel bicyclic heteroaryl derivative, a pharmaceutically acceptable salt thereof, a hydrate thereof, and a solvate thereof having an improved inhibitory activity for protein kinases, and a pharmaceutical composition for preventing or treating an abnormal cell growth disorder comprising same as an active ingredient.