131818-12-7

Basic information

• Product Name: O-benzyl 4-(2,5-dimethyl-1H-pyrrol-1-yl)-acetophenone oxime
• Synonyms: O-benzyl 4-(2,5-dimethyl-1H-pyrrol-1-yl)-acetophenone oxime
• CAS NO: 131818-12-7
• Molecular Weight: 318.418
• Mol File: 131818-12-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: O-benzyl 4-(2,5-dimethyl-1H-pyrrol-1-yl)-acetophenone oxime(CAS DataBase Reference)
• NIST Chemistry Reference: O-benzyl 4-(2,5-dimethyl-1H-pyrrol-1-yl)-acetophenone oxime(131818-12-7)
• EPA Substance Registry System: O-benzyl 4-(2,5-dimethyl-1H-pyrrol-1-yl)-acetophenone oxime(131818-12-7)

Safety Data

• Hazardous Substances Data: 131818-12-7(Hazardous Substances Data)

Upstream product

• 83935-45-9 4-(2,5-dimethyl-1H-pyrrol-1-yl)-acetophenone 
• 2687-43-6 O-benzylhydoxylamine hydrochloride 
• 7440-44-0 pyrographite 

Relevant articles and documents

PYRROLYLPHENYL-SUBSTITUTED HYDROXAMIC ACID DERIVATIVES

Disclosed are the pyrrolylphenyl-substituted hydroxamic acid derivatives of the formula wherein R represents hydrogen, lower alkyl, halogen or lower alkoxy; R1 and R2 independently represent hydrogen, lower alkyl or aryl; Y represents a direct bond, lower alkylene, lower alkenylene, lower alkadienylene, (thio, sulfinyl or sulfonyl)-lower alkylene or oxy-lower alkylene; Z represents wherein R3 represents hydrogen or acyl; R4 represents lower alkyl, C3-C7-cycloalkyl, aryl or aryl-lower alkyl; or Z represents wherein R3 represents hydrogen or acyl; R5 represents lower alkyl, C3-C7-cycloalkyl, aryl, aryl-lower alkyl, amino or N-(mono-or di-lower alkyl)-amino; R6 and R7 represent hydrogen or lower alkyl; and pharmaceutically acceptable salts thereof provided that R3 represents hydrogen; which are useful as selective lipoxygenase inhibitors, methods for preparation thereof, pharmaceutical compositions comprising said compounds, and a method of inhibiting lipoxygenase and of treating diseases in mammals which are responsive to lipoxygenase inhibition using said compounds and pharmaceutical compositions comprising said compounds of the invention.