13182-75-7

Basic information

• Product Name: 3-BENZYL[1,2,4]TRIAZOLO[3,4-B][1,3,4]THIADIAZOL-6-AMINE
• Synonyms: 3-BENZYL[1,2,4]TRIAZOLO[3,4-B][1,3,4]THIADIAZOL-6-AMINE;3-BENZYL[1,2,4]TRIAZOLO[3,4-B][1,3,4]THIADIAZOL-6-YLAMINE
• CAS NO: 13182-75-7
• Molecular Formula: C₁₀H₉N₅S
• Molecular Weight: 231.28
• Mol File: 13182-75-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-BENZYL[1,2,4]TRIAZOLO[3,4-B][1,3,4]THIADIAZOL-6-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BENZYL[1,2,4]TRIAZOLO[3,4-B][1,3,4]THIADIAZOL-6-AMINE(13182-75-7)
• EPA Substance Registry System: 3-BENZYL[1,2,4]TRIAZOLO[3,4-B][1,3,4]THIADIAZOL-6-AMINE(13182-75-7)

Safety Data

• Hazardous Substances Data: 13182-75-7(Hazardous Substances Data)

Upstream product

• 506-68-3 bromocyane 
• 13373-10-9 4-amino-2,4-dihydro-5-(phenylmethyl)-3H-1,2,4-triazole-3-thione 
• 13373-10-9 5-Benzyl-4-amino-3-mercapto-1,2,4-triazole 

Relevant articles and documents

Synthesis of Heterocycles. Part VII . Synthesis and Antimicrobial Activity of Some 7H-s-Triazolothiadiazine and s-Triazolothiadiazole Derivatives

The cyclization of 4-amino-5-aryl-3-cyanomethylthio-1,2,4-triazoles II in the presence of concentrated sulfuric acid yields 7H-6-amino-s-triazolothiadiazines III.Cyclization of 4-amino-5-aryl-1,2,4-triazole-3-thiones I with phenacyl chloride yields 7H-3-aryl-6-phenyl-s-triazolothiadiazines IV.Similarly, compounds I condensed with cyanogen bromide, phenyl isothiocyanate and carbon disulfide to give the corresponding cyclized products 6-amino-3-aryl-s-triazolothiadiazoles V, 3-aryl-6-phenylamino-s-triazolothiadiazoles VI and 3-aryl-s-triazolothiadiazol-6(5H)thiones VII, respectively.Also in the presence of phosphoryl chloride, compounds I underwent cyclization with monocarboxylic acids and oxalic acid to 3,6-diaryl-s-triazolothiadiazole VIII and 6,6'-bis(3-aryl-s-triazolothiadiazoles) IX.The above compounds were screened for their antimicrobial activity.