131864-67-0

Basic information

• Product Name: (R,R)-2,2'-(2,6-PYRIDINEDIYL)BIS(4-ISOPROPYL-2-OXAZOLINE)
• Synonyms: 2,6-bis((R)-4-isopropyl-4,5-dihydrooxazol-2-yl)pyridine;2,6-Bis[(4R)-(+)-isopropyl-2-oxazolin-2-yl]pyridine 99%;(+)-2,6-Bis[(4R)-4-(i-propyl)-2-oxazolin-2-yl]pyridine,97%;2,6-Bis[(4R)-isopropyl-2-oxazolin-2-yl]pyridine,99%e.e.;2,6-BIS[(4R)-(+)-ISOPROPYL-2-OXAZOLIN-2-YL]PYRIDINE;(+)-2,6-BIS[(4R)-4-(I-PROPYL)-2-OXAZOLIN-2-YL]PYRIDINE;(R,R)-2,6-BIS(4-ISOPROPYL-2-OXAZOLIN-2-YL)PYRIDINE;(R,R)-2,2'-(2,6-PYRIDINEDIYL)BIS(4-ISOPROPYL-2-OXAZOLINE)
• CAS NO: 131864-67-0
• Molecular Formula: C₁₇H₂₃N₃O₂
• Molecular Weight: 301.38
• Product Categories: Chiral Catalysts, Ligands, and Reagents;Privileged Ligands and Complexes;PyBOX;organic amine;BOX series;Chiral Nitrogen;Asymmetric Synthesis;Synthetic Organic Chemistry
• Mol File: 131864-67-0.mol
• Article Data: 0

Chemical Properties

• Melting Point: 154-156 °C(lit.)
• Boiling Point: 457.055 °C at 760 mmHg
• Flash Point: 230.219 °C
• Appearance: white/crystal
• Density: 1.233 g/cm³
• Vapor Pressure: 4.18E-08mmHg at 25°C
• Refractive Index: 118 ° (C=1, CH2Cl2)
• Storage Temp.: Refrigerator
• PKA: 3.78±0.70(Predicted)
• CAS DataBase Reference: (R,R)-2,2'-(2,6-PYRIDINEDIYL)BIS(4-ISOPROPYL-2-OXAZOLINE)(CAS DataBase Reference)
• NIST Chemistry Reference: (R,R)-2,2'-(2,6-PYRIDINEDIYL)BIS(4-ISOPROPYL-2-OXAZOLINE)(131864-67-0)
• EPA Substance Registry System: (R,R)-2,2'-(2,6-PYRIDINEDIYL)BIS(4-ISOPROPYL-2-OXAZOLINE)(131864-67-0)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 131864-67-0(Hazardous Substances Data)

Usage

Reaction

Ligand for enantioselective nitrone cycloaddition to α,β-unsaturated 2-acyl imidazoles. Highly efficient catalytic enantioselective Mannich reaction of malonates with N-tert-butoxycarbonyl imines.

Chemical Properties

White powder

Uses

C2 symmetric ligand for enantioselective catalysis. Easily forms bidentate coordination complexes due to the strong affinity of the oxazoline nitrogen for various metals.

InChI:InChI=1/C17H23N3O2/c1-10(2)14-8-21-16(19-14)12-6-5-7-13(18-12)17-20-15(9-22-17)11(3)4/h5-7,10-11,14-15H,8-9H2,1-4H3/t14-,15-/m0/s1