1318782-25-0Relevant articles and documents
Novel β-amino acid derivatives as inhibitors of cathepsin A
Ruf, Sven,Buning, Christian,Schreuder, Herman,Horstick, Georg,Linz, Wolfgang,Olpp, Thomas,Pernerstorfer, Josef,Hiss, Katrin,Kroll, Katja,Kannt, Aimo,Kohlmann, Markus,Linz, Dominik,Hübschle, Thomas,Rütten, Hartmut,Wirth, Klaus,Schmidt, Thorsten,Sadowski, Thorsten
, p. 7636 - 7649 (2012/11/07)
Cathepsin A (CatA) is a serine carboxypeptidase distributed between lysosomes, cell membrane, and extracellular space. Several peptide hormones including bradykinin and angiotensin I have been described as substrates. Therefore, the inhibition of CatA has