13188-55-1Relevant articles and documents
Two polymorphic forms of 2,5-bis-(4-methoxycarbonylphenyl)-1,3,4-oxadiazole
Reck, Guenter,Orgzall, Ingo,Schulz, Burkhard,Dietzel, Birgit
, p. o634-o635 (2003)
The title compound [systematic name: dimethyl 4,4′-(1,3,4-oxadiazole-2,5-diyl)diphenylenedicarboxylate], C18H14N2O5, crystallizes under similar conditions in two different orthorhombic crystalline forms. In both
Discovery of Novel Small-Molecule Inhibitors of NF-κB Signaling with Antiinflammatory and Anticancer Properties
Zhang, Lei,Shi, Lei,Soars, Shafer Myers,Kamps, Joshua,Yin, Hang
, p. 5881 - 5899 (2018/06/13)
Excessive NF-κB activation contributes to the pathogenesis of numerous diseases. Small-molecule inhibitors of NF-κB signaling have significant therapeutic potential especially in treating inflammatory diseases and cancers. In this study, we performed a ce
Discovery of highly selective and potent monoamine oxidase B inhibitors: Contribution of additional phenyl rings introduced into?2-aryl-1,3,4-oxadiazin-5(6H)-one
Lee, Jungeun,Lee, Yeongcheol,Park, So Jung,Lee, Joohee,Kim, Yeong Shik,Suh, Young-Ger,Lee, Jeeyeon
, p. 365 - 378 (2017/03/10)
Monoamine oxidase B (MAO-B) is a flavin adenine dinucleotide (FAD)-containing enzyme that plays a major role in the oxidative deamination of biogenic amines and neurotransmitters. Inhibiting MAO-B activity is a promising approach in the treatment of neuro