131887-70-2Relevant articles and documents
Structure-activity relationship study of the bacterial actin-like protein MreB inhibitors: Effects of substitution of benzyl group in S-benzylisothiourea
Iwai, Noritaka,Fujii, Takuya,Nagura, Hirokatsu,Wachi, Masaaki,Kitazume, Tomoya
, p. 246 - 248 (2008/03/13)
We comprehensively investigated the effects of substitution of the benzyl group in S-benzylisothiourea derivatives on antibacterial activity, because we found previously that some substitutions enhanced it. A 2,4-Cl 2-derivative was found to be the most effective compound, it was stronger than the original one in Gram-negative rod shaped-bacteria such as Escherichia coli and Salmonella typhimurium.