1319719-25-9

Basic information

• Product Name: (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl-2?(4?(4-chlorobenzoyl)phenoxy)-2-methylpropanoate
• Synonyms: (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl-2?(4?(4-chlorobenzoyl)phenoxy)-2-methylpropanoate
• CAS NO: 1319719-25-9
• Molecular Weight: 430.842
• Mol File: 1319719-25-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl-2?(4?(4-chlorobenzoyl)phenoxy)-2-methylpropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl-2?(4?(4-chlorobenzoyl)phenoxy)-2-methylpropanoate(1319719-25-9)
• EPA Substance Registry System: (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl-2?(4?(4-chlorobenzoyl)phenoxy)-2-methylpropanoate(1319719-25-9)

Safety Data

• Hazardous Substances Data: 1319719-25-9(Hazardous Substances Data)

Upstream product

• 122-01-0 4-chloro-benzoyl chloride 
• 100-66-3 methoxybenzene 
• 49562-28-9 fenofibrate 
• 42019-78-3 4-chloro-4'-hydroxybenzophenone 
• 42017-89-0 fenofibric acid 
• 80841-78-7 4-chloromethyl-5-methyl-1,3-dioxol-2-one 

Relevant articles and documents

Synthesis and evaluation of fenofibric acid ester derivatives: Studies of different formulation with their bioavailability and absorption conditions

A series of fenofibric acid ester pro-drugs (JF-1-7) were synthesized. The pharmacokinetic properties of these pro-drugs were examined after oral administration to rats at a dose of 20 mg kg-1 to evaluate the relative bioavailability in rats. The bioavailability of the ester compounds, JF-1, 2, 3, 4, 5, 6, and 7, was significantly higher than that of fenofibrate. In particular, JF-2 proved to be most promising. The oral administration (20 mg kg-1) of JF-2 showed a relative bioavailability of approximately 272.8percent compared to fenofibrate.