1319736-51-0

Basic information

• Product Name: (4R)-4-((S)-1-hydroxyethyl)-1-((R)-1-phenylethyl)pyrrolidine-2-one
• Synonyms: (4R)-4-((S)-1-hydroxyethyl)-1-((R)-1-phenylethyl)pyrrolidine-2-one
• CAS NO: 1319736-51-0
• Molecular Weight: 233.31
• Mol File: 1319736-51-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (4R)-4-((S)-1-hydroxyethyl)-1-((R)-1-phenylethyl)pyrrolidine-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4R)-4-((S)-1-hydroxyethyl)-1-((R)-1-phenylethyl)pyrrolidine-2-one(1319736-51-0)
• EPA Substance Registry System: (4R)-4-((S)-1-hydroxyethyl)-1-((R)-1-phenylethyl)pyrrolidine-2-one(1319736-51-0)

Safety Data

• Hazardous Substances Data: 1319736-51-0(Hazardous Substances Data)

Upstream product

• 269407-03-6 (R)-N-methoxy-N-methyl-5-oxo-1-((R)-1-phenylethyl)pyrrolidine-3-carboxamide 
• 99735-43-0 (3R)-1-((R)-1-phenylethyl)-5-oxo-3-pyrrolidinecarboxylic acid 
• 1319736-57-6 (R)-N-methoxy-5-oxo-1-((R)-1-phenylethyl)pyrrolidine-3-carboxamide 
• 146511-96-8 (R)-4-acetyl-1-((R)-1-phenylethyl)pyrrolidine-2-one 

Downstream Products

• 1421339-70-9 (R)-4-((R)-1-(7-phenylquinolin-5-yloxy)ethyl)pyrrolidin-2-one 
• 1421341-20-9 C₂₉H₂₈N₂O₂ 
• 1421339-71-0 (R)-4-((R)-1-(7-(3,4,5-trimethoxyphenyl)quinolin-5-yloxy)ethyl)pyrrolidin-2-one 
• 1421341-21-0 C₃₂H₃₄N₂O₅ 

Relevant articles and documents

SYK INHIBITORS

The present disclosure a Syk compound inhibitors, including state cancer and inflammation and various disease States thereof in the treatment of relates to the use of. In one aspect a particular embodiment, . given by formula I which is marked as a chemical structure of compound. In formula said, X 1, X 2, X 3, R 2, R 3, R 4, R 5, and Y has described herein is. The present disclosure of a formula I compounds or a pharmaceutically acceptable salt of pharmaceutical compositions including, mediated by Syk and to treat conditions a employing these compounds and compositions further provides a method. (by machine translation)

Substituted Quinolines and Their Use As Medicaments

Disclosed are substituted quinolines of formula 1 wherein R1 and R2 are defined herein, the processing of making and using the same.

SUBSTITUTED NAPHTHYRIDINES AND THEIR USE AS SYK KINASE INHIBITORS

The invention relates to new substituted naphthyridines of formula (1), as well as pharmacologically acceptable salts, diastereomers, enantiomers, racemates, hydrates or solvates thereof, wherein R1 is selected from among -O-R3 or -NR3R4, R3 is C1-6-alkyl which is substituted by R5 and R6 R5 is selected from hydrogen, branched or linear C1-6-alkyl, C2-6-alkenyl, -C1-6-alkylen-O-C1-3-alkyl, C1-3-haloalkyl, R6 is ring X wherein n is either 0 or 1, and Formula (I) is a either a single or a double bond and wherein A, B, D and E are each independently from one another selected from CH2, CH, C, N, NH, O or S and wherein ring X is attached to the molecule either via position A, B, D or E, wherein said ring X may optionally be further substituted by one, two or three residues each selected individually from the group consisting of -oxo, hydroxy, -C1-3-alkyl, -C1-3-haloalkyl, -O-C1-3-alkyl, -C1-3-alkanol and halogen, and wherein R4, R2, R7, R8, R9, R10, R11 and Q may have the meanings as given in claim 1, as well as pharmaceutical compositions containing these compounds.