1320-66-7 Usage
Description
Chlorobutanol, also known as Chlorobutanol Hemihydrate, is a chemical compound with the chemical formula C10H17ClO2. It is a crystalline solid with a camphor-like odor and taste, and it sublimes. Chlorobutanol has a melting point of 97°C (206°F) and a boiling point of 167°C (332°F). It is soluble in water and organic solvents and is commonly known by the brand name Chloretone (Parke-Davis).
Uses
1. Used in Pharmaceutical Industry:
Chlorobutanol is used as an antimicrobial agent for preserving hypodermic solutions and in veterinary medicine as a mild sedative and antiseptic.
2. Used in Plastic Industry:
Chlorobutanol is used as a plasticizer for cellulose esters, enhancing the flexibility and workability of the material.
3. Used in Veterinary Medicine:
Chlorobutanol serves as a mild sedative and antiseptic, providing calming effects and preventing infection in animals.
Health Hazard
Chlorobutanol exhibited moderate toxicity intest animals. A lethal dose by oral intake indogs and rabbits were 238 and 213 mg/kg,respectively (NIOSH 1986). The toxic symptoms are not reported. This compound isa mild skin and eye irritant and may bemutagenic.
Clinical Use
1,1,1-Trichloro-2-methyl-2-propanol is a white crystallinesolid with a camphorlike aroma. It occurs in an anhydrousform and a hemihydrate form, both of which sublime at roomtemperature and pressure. Chlorobutanol is slightly soluble inwater and soluble in alcohol and in organic solvents.Chlorobutanol is used as a bacteriostatic agent in pharmaceuticalsfor injection, ophthalmic use, and intranasal administration.It is unstable when heated in aqueous solution, especially at pH greater than 7. Under these conditions,chlorobutanol undergoes elimination. Solutions with a pHof approximately 5 are reasonably stable at 25°C.Chlorobutanol is stable in oils and organic solvents.
Waste Disposal
A suitable method of destruction of chlorobu tanol is the burning of its solution in a com bustible solvent in a chemical incinerator.
Check Digit Verification of cas no
The CAS Registry Mumber 1320-66-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,3,2 and 0 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1320-66:
(6*1)+(5*3)+(4*2)+(3*0)+(2*6)+(1*6)=47
47 % 10 = 7
So 1320-66-7 is a valid CAS Registry Number.
InChI:InChI=1/C4H7Cl3O/c1-3(2,8)4(5,6)7/h8H,1-2H3
