132101-64-5

Basic information

• Product Name: 3-methyl-3-(tetrahydro-2H-pyran-2-yloxy)butyne
• CAS NO: 132101-64-5
• Molecular Weight: 168.236
• Mol File: 132101-64-5.mol
• Article Data: 27

Chemical Properties

• CAS DataBase Reference: 3-methyl-3-(tetrahydro-2H-pyran-2-yloxy)butyne(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methyl-3-(tetrahydro-2H-pyran-2-yloxy)butyne(132101-64-5)
• EPA Substance Registry System: 3-methyl-3-(tetrahydro-2H-pyran-2-yloxy)butyne(132101-64-5)

Safety Data

• Hazardous Substances Data: 132101-64-5(Hazardous Substances Data)

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 115-19-5 2-methyl-but-3-yn-2-ol 

Downstream Products

• 1637401-85-4 3-diphenylphosphinoyl-2,5-dimethylnona-3,4-dien-2-ol 
• 1637401-84-3 3-diphenylphosphinoyl-2,5-dimethylhepta-3,4-dien-2-ol 
• 1637401-69-4 2-(2-diphenylphosphinoyl-1,1,4-trimethyl-octa-2,3-dienyloxy)-tetrahydro-2H-pyran 
• 1637401-68-3 2-(2-diphenylphosphinoyl-1,1,4-trimethyl-hexa-2,3-dienyloxy)-tetrahydro-2H-pyran 
• 1379935-91-7 1-benzyl-3-acetyl-3-allyl-4-(2-methylprop-1-en-1-yl)pyrrolidin-2-one 
• 1379935-80-4 N-benzyl-N-(4-methylpenta-2,3-dien-1-yl)-2-acetylpent-4-enamide 
• 1379935-71-3 N-benzyl-4,4-dimethyl-N-(4-methylpenta-2,3-dien-1-yl)-3-oxopentanamide 
• 1379935-62-2 N-benzyl-N-(4-methylpenta-2,3-dien-1-yl)-2-acetylacetamide 
• 1379935-52-0 N-benzyl(4-methylpenta-2,3-dienyl)trifluoroacetamide 
• 1379935-48-4 4-methylpenta-2,3-dienyl 2-phenylacetate 
• 1205051-11-1 tetrahydro-2-[[4-(2-bromophenyl)-2-methyl-3-butyn-2-yl]oxy]-2H-pyran 

Relevant articles and documents

Total synthesis of spatol and other spatane diterpenes

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Mercury in Organic Chemistry. 24. Mercuration and Subsequent Carbonylation of 4-Hydroxy-2-alkyn-1-ones: A Novel Route to Furans

Mercuric chloride readily adds to the carbon-carbon triple bond of certain 4-hydroxy-2-alkyn-1-ones (3a, 3b, and 3e) to give vinylmercurials which appear to be the first syn addition compounds of mercuric chloride.These vinylmercurials readily dehydrate to 3-furylmercurials.Palladium-promoted carbonylation of these compounds affords 3-furyl carbonyl compounds.

Designing the Molybdopterin Core through Regioselective Coupling of Building Blocks

Molybdopterin is an essential cofactor for all forms of life. The cofactor is composed of a pterin moiety appended to a dithiolene-functionalized pyran ring, and through the dithiolene moiety it binds metal ions. Different synthetic strategies for dithiolene-functionalized pyran precursors that have been designed and synthesized are discussed. These precursors also harbor 1,2-diketone or osone functionality that has been condensed with 1,2-diaminobenzene or other heterocycles resulting in several quinoxaline or pterin derivatives. Use of additives improves the regioselectivity of the complexes. The molecules have been characterized by 1H and 13C NMR and IR spectroscopies, as well as by mass spectrometry. In addition, several compounds have been crystallographically characterized. The geometries of the synthesized molecules are more planar than the geometry of the cofactor found in proteins.

Gold-catalyzed N, O-functionalizations of 6-allenyl-1-ynes with n-hydroxyanilines to construct benzo[b]-azepin-4-one cores

Gold-catalyzed reactions of 6-allen-1-ynes with N-hydroxyanilines afford thermally stable benzoazepin-4-ones in anti-selectivity; these anti-configured products are easily isomerized to their syn-isomers on a silica column. The mechanism of reactions likely involve initial nitrone/allene cycloadditions, followed by skeletal rearrangement of resulting intermediates.

Regioselective Rh-Catalyzed Hydroformylation of 1,1,3-Trisubstituted Allenes Using BisDiazaPhos Ligand

The efficient hydroformylation of 1,1,3-trisubstituted allenes is accomplished with low loadings of a Rh catalyst supported by a BisDiazaPhos (BDP) ligand. The ligand identity is key to achieving high regioselectivity, while the mild reaction conditions m