132201-33-3Relevant articles and documents
1,3-Dipolar cycloadditions of carbonyl ylides to aldimines: A three-component approach to syn-α-hydroxy-β-amino esters
Torssell, Staffan,Kienle, Marcel,Somfai, Peter
, p. 3096 - 3099 (2005)
(Chemical Equation Presented) A highly diastereoselective Rh II-catalyzed 1,3-dipolar cycloaddition leads to the formation of syn-β-amino alcohols and syn-α-hydroxy-β-amino acids in high yields (see scheme; p-TSA = poro-toluenesulfonic acid, Bn = benzyl). This three-component approach to the addition of metal-associated carbonyl ylides to aldimines was applied to a short enantioselective synthesis of the C13 side chain of taxol.
Synthesis and biological activity of C-7, C-9 and C-10 modified taxane analogues from 1-deoxybaccatin VI
Cui, Yongmei,Li, Lanlan,Lin, Haixia,Liu, Hongchun,Xie, Chenghu,Zhang, Minmin
, (2020)
A series of C-7, C-9 and C-10 modified taxane analogues were synthesized and their in vitro anticancer activities against three human cancer cell lines: A-549 (human lung cancer cell line), MDA-MB-231 (human breast cancer cell line), A-549/T (human lung c
N-benzoyl phenylisoserine derivative as well as synthesis method and application thereof
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Paragraph 0116-0119, (2019/09/14)
The invention discloses an N-benzoyl phenylisoserine derivative and a synthesis method thereof. N-benzoyl phenylimine, a diazo compound and isopropyl aldehyde are taken as raw materials, a molecular sieve is taken as a water absorbing agent, rhodium aceta
Chiral Manganese Aminopyridine Complexes: the Versatile Catalysts of Chemo- and Stereoselective Oxidations with H2O2
Ottenbacher, Roman V.,Talsi, Evgenii P.,Bryliakov, Konstantin P.
, p. 78 - 90 (2017/10/06)
In the last decade, manganese(II) complexes with N-donor tetradentate aminopyridine ligands emerged as efficient catalysts of enantioselective epoxidation of olefins and direct selective oxidation of C?H groups in complex organic molecules, with environmentally benign oxidant hydrogen peroxide. In this personal account, we summarize the progress of these catalysts with regard to ligands design, structure-reactivity correlations, evaluation of the substrate scope, as well as mechanistic studies, shedding light on the nature of active sites and the mechanisms of selective oxygenations. Several practically promising catalytic syntheses with the aid of Mn aminopyridine catalysts are exemplified.
