132244-31-6

Basic information

• Product Name: 5-BROMO-BENZOOXAZOLE
• Synonyms: 5-BROMO-BENZOOXAZOLE;5-BROMOBENZOXAZOLE;CHEMBRDG-BB 4002139;5-BROMO-1,3-BENZOXAZOLE;5-BROMOBENZO[D]OXAZOLE;5-BROMOBENZO[D]OXAZOLE ,97%;5-bromo-1,3-benzoxazole(SALTDATA: FREE);Benzoxazole, 5-broMo-
• CAS NO: 132244-31-6
• Molecular Formula: C₇H₄BrNO
• Molecular Weight: 198.01676
• Product Categories: Miscellaneous
• Mol File: 132244-31-6.mol
• Article Data: 16

Chemical Properties

• Melting Point: 38-40°
• Boiling Point: 251.169 °C at 760 mmHg
• Flash Point: 105.704 °C
• Appearance: /
• Density: 1.711g/cm³
• Vapor Pressure: 0.033mmHg at 25°C
• Refractive Index: 1.649
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: soluble in Methanol
• PKA: -0.85±0.10(Predicted)
• CAS DataBase Reference: 5-BROMO-BENZOOXAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-BENZOOXAZOLE(132244-31-6)
• EPA Substance Registry System: 5-BROMO-BENZOOXAZOLE(132244-31-6)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26
• WGK Germany: 3
• HazardClass: IRRITANT
• Hazardous Substances Data: 132244-31-6(Hazardous Substances Data)

Usage

General Description

5-Bromo-Benzooxazole is a chemical compound that belongs to the organohalogen compound class and specifically to the benzoxazoles subclass. It is characterized by a benzoxazole core structure with a bromine atom attached. The systematic name for this compound is 5-bromo-1,3-benzoxazole. It appears as an off-white to light yellow crystalline solid with a molecular weight of about 198.02 g/mol. 5-Bromo-Benzooxazole is often used in chemical and pharmaceutical research as a raw material or reagent, demonstrating potential utility in the synthesis of a variety of chemical compounds. The chemical stability, reactivity, and potential hazards of 5-Bromo-Benzooxazole, like many chemicals, will vary based on the specific conditions and environments of use.

InChI:InChI=1/C7H4BrNO/c8-5-1-2-7-6(3-5)9-4-10-7/h1-4H

Upstream product

• 40925-68-6 2-amino-4-bromo-phenol 
• 122-51-0 orthoformic acid triethyl ester 
• 149-73-5 trimethyl orthoformate 
• 95-56-7 2-hydroxybromobenzene 
• 7693-52-9 4-bromo-2-nitrophenol 
• 106-41-2 4-bromo-phenol 
• 124-38-9 carbon dioxide 

Downstream Products

• 628710-98-5 4-methoxy-3-(benzoxazol-5-yl)benzenecarboxyaldehyde 
• 1008361-50-9 4-(1,3-benzoxazol-5-yl)benzaldehyde 
• 1263075-35-9 N-(2-hydroxy-5-(5-(2-methoxyethylamino)-3-methyl-4-oxo-3,4-dihydropyrido[4,3-d]pyrimidin-7-yl)phenyl)formamide 
• 375369-08-7 5-bromo-2-(trifluoromethyl)benzo[d]oxazole 
• 1383324-92-2 5-bromo-2-(1,2,3-triphenylpropan-2-yl)benzo[d]oxazole 
• 1383325-03-8 5-bromo-2-(1,2-diphenylethyl)benzo[d]oxazole 
• 915921-41-4 2-benzyl-5-bromobenzo[d]oxazole 
• 954239-61-3 5-bromo-benzoxazole-2-carboxylic acid methyl ester 
• 944898-52-6 5-bromo-1,3-benzoxazole-2-carboxylic acid 
• 69918-19-0 5-bromo-2-phenylbenzo[d]oxazole 
• 1427691-01-7 (1,3-benzoxazol-5-yl)(3,4,5-trimethoxyphenyl)methanol 
• 1427691-02-8 C₁₇H₁₅NO₅ 
• 1598429-83-4 C₁₄H₈BrNO₂ 
• 1638125-49-1 (5-bromobenzo[d]oxazol-2-yl)(phenyl)methanone 

Relevant articles and documents

Cobalt-catalyzed synthesis of N-containing heterocycles: Via cyclization of ortho -substituted anilines with CO2/H2

The CO2-involved synthesis of chemicals is of great significance from the green and sustainable chemistry viewpoint. Herein, we report a non-noble metal catalytic system composed of CoF2, CsF and P(CH2CH2PPh2)3 (denoted as PP3) for the synthesis of N-containing heterocycles from ortho-substituted anilines and CO2/H2. Mechanism investigation indicates that [Co(PP3)H(CO2)]+ is a catalytically active intermediate under working conditions; and CsF plays important roles in activating ortho-substituted anilines via hydrogen bond interactions, thus promoting the formation of the final products. This catalytic system is highly efficient, and allows a wide scope of ortho-substituted anilines, together with excellent functional group tolerance, affording various N-containing heterocycles in good to excellent yields.

1,8-NAPHTHYRIDINONE COMPOUNDS AND USES THEREOF

1,8-naphthyridinone compounds as modulators of an adenosine receptor are provided. The compounds may find use as therapeutic agents for the treatment of diseases mediated through a G-protein-coupled receptor signaling pathway and may find particular use in oncology.

Benzoxazoles as Selective Monoamine Oxidase B (MAO-B) Inhibitors

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