132248-58-9 Usage
Description
2,2,2-Trifluoroethanol-1,1-d2 (2,2,2-Trifluoroethyl-1,1-d2 alcohol, TFE-d2) is a deuterated form of trifluoroethanol, a compound that is commonly used as a solvent in nuclear magnetic resonance (NMR) spectroscopy. This deuterated version is particularly valuable for scientific research and analysis, as the presence of deuterium (D2) isotopes can provide enhanced spectral resolution and reduce interference from background signals.
Uses
Used in NMR Spectroscopy:
2,2,2-Trifluoroethanol-1,1-d2 is used as a solvent in NMR spectroscopy for enhancing the resolution of spectral data. The incorporation of deuterium isotopes in the molecule allows for clearer identification and analysis of chemical structures and interactions within the sample being studied.
Used in Chemical Research:
In the field of chemical research, 2,2,2-Trifluoroethanol-1,1-d2 is utilized as a reagent or solvent to facilitate specific reactions or to study the properties of various compounds. Its unique characteristics, including its deuterated nature, make it a valuable tool for probing molecular interactions and understanding reaction mechanisms.
Used in Pharmaceutical Development:
2,2,2-Trifluoroethanol-1,1-d2 can be employed in the pharmaceutical industry for the development of new drugs and the study of drug candidates. Its use in NMR spectroscopy aids in the detailed analysis of drug molecules, which is crucial for optimizing their efficacy and safety.
Used in Material Science:
In material science, 2,2,2-Trifluoroethanol-1,1-d2 may be used to study the properties of new materials or to assist in the synthesis of advanced materials with specific characteristics. Its application in NMR spectroscopy provides insights into the molecular structure and dynamics of these materials, which can be critical for their development and application.
Check Digit Verification of cas no
The CAS Registry Mumber 132248-58-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,2,4 and 8 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 132248-58:
(8*1)+(7*3)+(6*2)+(5*2)+(4*4)+(3*8)+(2*5)+(1*8)=109
109 % 10 = 9
So 132248-58-9 is a valid CAS Registry Number.
InChI:InChI=1/C2H3F3O/c3-2(4,5)1-6/h6H,1H2/i1D2
132248-58-9Relevant articles and documents
Reversible and Irreversible ElcB Mechanisms in the Hydrolysis of 2,2,2-Trifluoroethanesulfonyl Chloride: Carbanion Intermediates in Aqueous Acid
King, James F.,Gill, Manjinder Singh
, p. 808 - 811 (2007/10/03)
Hydrolysis of 2,2,2-trifluoroethanesulfonyl chloride (1) is shown to take place by way of the sulfene (CF3CH=SO2), formed by (a) an irreversible E1cB process over the pH range 1.8-5 with water acting as the carbanion-forming base in the lower pH range and hydroxide anion at higher pH, and (b) a reversible E1cB reaction in dilute acid.
