132274-45-4

Basic information

• Product Name: 2-(4-Methoxyphenyl)-2-(trimethylsilyl)-1,3-dithiane
• Synonyms: 2-(4-Methoxyphenyl)-2-(trimethylsilyl)-1,3-dithiane
• CAS NO: 132274-45-4
• Molecular Weight: 298.546
• Mol File: 132274-45-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-(4-Methoxyphenyl)-2-(trimethylsilyl)-1,3-dithiane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Methoxyphenyl)-2-(trimethylsilyl)-1,3-dithiane(132274-45-4)
• EPA Substance Registry System: 2-(4-Methoxyphenyl)-2-(trimethylsilyl)-1,3-dithiane(132274-45-4)

Safety Data

• Hazardous Substances Data: 132274-45-4(Hazardous Substances Data)

Upstream product

• 23837-15-2 1-(bis(ethylthio)methyl)-4-methoxybenzene 
• 6712-20-5 2-(4-methoxyphenyl)-[1,3]dithiolane 
• 123-11-5 4-methoxy-benzaldehyde 
• 75-77-4 chloro-trimethyl-silane 
• 24588-72-5 2-(4-methoxyphenyl)-1,3-dithiane 

Downstream Products

• 6968-77-0 3-(4-methoxyphenyl)-2-phenylacrylic acid 
• 846541-57-9 3t-(4-methoxy-phenyl)-2,3c-diphenyl-acrylic acid 
• 1671-76-7 p-Methoxyvalerophenon 
• 611-94-9 4-Methoxybenzophenone 
• 75748-09-3 (4-methoxybenzoyl)trimethylsilane 

Relevant articles and documents

Oxidative [1,2]-Brook Rearrangements Exploiting Single-Electron Transfer: Photoredox-Catalyzed Alkylations and Arylations

Oxidative [1,2]-Brook rearrangements via hypervalent silicon intermediates induced by photoredox-catalyzed single-electron transfer have been achieved, permitting the formation of reactive radical species that can engage in alkylations and arylations.

Palladium-catalyzed fluoride-free cross-coupling of intramolecularly activated alkenylsilanes and alkenylgermanes: Synthesis of tamoxifen as a synthetic application

We have demonstrated that intramolecular hypercoordination of a carboxylic acid is a powerful activation strategy for the palladium-catalyzed cross-coupling reaction of trialkyl(vinyl)silanes and trialkyl(vinyl)germanes under fluoride-free conditions. Z-β-Trialkylsilyl- and Z-β- trialkylgermylacrylic acids, synthesized stereoselectively by olefination with ynolates, are highly stable and useful reagents for cross-coupling with a variety of aryl iodides to provide tetrasubstituted olefins possessing different carbon substituents in a stereocontrolled and diversity-oriented manner. An application to a stereoselective synthesis of (Z)-tamoxifen is also reported. Copyright

Enantioselective synthesis of a-hydroxysilanes by bioreduction of aroyltrimcthylsilanes

Aromatic acylsilanes [Ar-CO-SiMe3; Ar = C6H5,4-ClC6H4, 2-, 3- and 4-OMeC6H4, 3,4-(OMe)2C6H3 and 3,4-OCH2OC6H3] were reduced by baker's yeast to optically active a-silyl alcohols in 20-70% yield and 43-88% ee. Comments are made on the influence of silicon in this bioreduction reaction. The Royal Society of Chemistry 1999.