132286-13-6Relevant articles and documents
Acetoacetoxy ethyl methacrylate (AAEM) resin, a new scavenger for primary amines in the presence of secondary amines
Yu, Zhanru,Alesso, Sonia,Pears, David,Worthington, Paul A.,Luke, Richard W.A.,Bradley, Mark
, p. 8963 - 8967 (2000)
Preliminary results on a new type of polymer scavenger, acetoacetoxy ethyl methacrylate (AAEM) resin, are reported. AAEM resin can selectively remove primary amines in the presence of secondary amines. Its application in a solution library synthesis is demonstrate. (C) 2000 Elsevier Science Ltd.
Ketoester methacrylate resin, secondary amine clean-up in the presence of primary amines
Yu,Alesso,Pears,Worthington,Luke,Bradley
, p. 1947 - 1952 (2007/10/03)
A ketoester resin was developed as the basis for a selective scavenger for primary amines in the presence of secondary amines. The utility of the scavenger was demonstrated with a range of reductive amination chemistries with both mono- and diamines. The resin's specificity is based on the removal of the primary amines via their enamines.
Antihyperlipidemic and antiatherosclerotic trisubstituted urea compounds
-
, (2008/06/13)
Certain trisubstituted urea compounds as potent inhibitors of the enzyme acyl-CoA:cholesterol acyltransferase, their method of manufacture, pharmaceutical compositions containing such compounds as well as methods of inhibiting the interstitial absorption of cholesterol and lowering blood plasma cholesterol with such compounds as described.