132339-28-7

Basic information

• Product Name: (1S,1'R,2R,2'S,5S,5'R)-1,1'-methylenedioxybis(2-isopropyl-5-methylcyclohexane)
• Synonyms: (1S,1'R,2R,2'S,5S,5'R)-1,1'-methylenedioxybis(2-isopropyl-5-methylcyclohexane)
• CAS NO: 132339-28-7
• Molecular Weight: 324.547
• Mol File: 132339-28-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (1S,1'R,2R,2'S,5S,5'R)-1,1'-methylenedioxybis(2-isopropyl-5-methylcyclohexane)(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,1'R,2R,2'S,5S,5'R)-1,1'-methylenedioxybis(2-isopropyl-5-methylcyclohexane)(132339-28-7)
• EPA Substance Registry System: (1S,1'R,2R,2'S,5S,5'R)-1,1'-methylenedioxybis(2-isopropyl-5-methylcyclohexane)(132339-28-7)

Safety Data

• Hazardous Substances Data: 132339-28-7(Hazardous Substances Data)

Upstream product

• 89-78-1 menthol 
• 67-68-5 dimethyl sulfoxide 
• 2216-51-5 (-)-menthol 
• 91898-15-6 1-Isopropyl-2-(2-methoxy-ethoxymethoxy)-4-methyl-cyclohexane 
• 50-00-0 formaldehyd 
• 103128-76-3 (1S,2R,4S)-2-(chloromethyloxy)-1-isopropyl-4-methylcyclohexane 
• 26127-08-2 (1R,2S,5R)-1-(chloromethoxy)-2-isopropyl-5-methylcyclohexane 
• 15356-70-4 menthol 
• 15356-60-2 (1S,2R,5S)-(+)-menthol 

Downstream Products

• 15356-70-4 menthol 
• 1463902-01-3 C₂₁H₃₄O₃ 
• 26127-08-2 (1R,2S,5R)-1-(chloromethoxy)-2-isopropyl-5-methylcyclohexane 
• 1463901-93-0 C₁₇H₂₆O₂ 
• 1463901-95-2 C₁₇H₂₅BrO₂ 
• 1463901-97-4 C₂₄H₃₂O₃ 
• 1463901-99-6 C₂₀H₃₂O₃ 

Relevant articles and documents

Dimethyl sulfoxide as a "methylene" source: Ru(ii) photo-catalysed facile synthesis of acetals from alcohols

Acetals are important molecules with versatile reactivity and uses. For the first time a simple photo-catalysed facile synthesis of formaldehyde acetals is documented herein upon the reaction of alcohols with dimethyl sulfoxide under very mild conditions in the presence of air. The reactions require only 1 mol% of RuII(bpy)3Cl2 photocatalyst under blue LED irradiation (λ = 445 nm) to give good to excellent yields of the corresponding acetal products. Here DMSO acts as a "methylene" source.

Preparation and Use of Chloromethyl (-)-Menthyl Ether in the Synthesis of Optically Pure α-Branched α-Amino Nitriles

The synthesis of optically pure chloromethyl (-)-menthyl ether (2b) and its use in the synthesis of di-(-)-menthyl acetal (-)-menthyl (+)-menthyl acetals are described.The diastereomeric mixed acetals 7a,b and 8a,b are easily obtainable from the nitrones 5 and 6, KCN and 2b.The mixture of diastereomers are separated into the pure components 7a, 7b and 8a, 8b by simple silica gel column chromatography.Hydrolysis of these products (H2O2/Na2CO3, ultrasound) followed by N-O cleavage affords the heterocyclic α-methyl-α-amino amides 11a, 11b and 12a, 12b.These are subsequently hydrolyzed to give the corresponding α-methyl-α-amino acids with S and R configuration, respectively.