13254-07-4

Basic information

• Product Name: Z-ILE-PHE-OH
• Synonyms: Z-ILE-PHE-OH;Z-L-ISOLEUCYL-L-PHENYLALANINE;CBZ-L-ILE-PHE;N-cbz-ile-phe;3-phenyl-N-[N-[(phenylmethoxy)carbonyl]-L-isoleucyl]-L-alanine;Z-lle-Phe-OH;N-carbobenzyloxy-Ile-Phe;N-[N-[(Phenylmethoxy)carbonyl]-L-isoleucyl]-L-phenylalanine
• CAS NO: 13254-07-4
• Molecular Formula: C₂₃H₂₈N₂O₅
• Molecular Weight: 412.48
• EINECS: 236-242-0
• Mol File: 13254-07-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 166-167 °C
• Boiling Point: 654.9 °C at 760 mmHg
• Flash Point: 349.9 °C
• Appearance: /
• Density: 1.193 g/cm³
• Vapor Pressure: 4.78E-18mmHg at 25°C
• Refractive Index: 1.564
• Storage Temp.: -15°C
• PKA: 3.54±0.10(Predicted)
• CAS DataBase Reference: Z-ILE-PHE-OH(CAS DataBase Reference)
• NIST Chemistry Reference: Z-ILE-PHE-OH(13254-07-4)
• EPA Substance Registry System: Z-ILE-PHE-OH(13254-07-4)

Safety Data

• Hazardous Substances Data: 13254-07-4(Hazardous Substances Data)

Usage

General Description

Z-ILE-PHE-OH, also known as Isoleucyl-phenylalanine, is a dipeptide comprised of isoleucine and phenylalanine, two amino acids necessary for the proper development and functioning of the human body. Isoleucine is an essential amino acid, crucial for hemoglobin production and regulating blood sugar and energy levels, while phenylalanine plays a vital role in the structure and function of proteins and enzymes and the production of other amino acids. Z-ILE-PHE-OH is typically used in scientific research, particularly in studies focusing on metabolic function, protein synthesis, and enzymatic processes.

InChI:InChI=1/C23H28N2O5/c1-3-16(2)20(25-23(29)30-15-18-12-8-5-9-13-18)21(26)24-19(22(27)28)14-17-10-6-4-7-11-17/h4-13,16,19-20H,3,14-15H2,1-2H3,(H,24,26)(H,25,29)(H,27,28)/t16-,19-,20-/m0/s1

Upstream product

• 3160-59-6 N-Cbz-L-Isoleucine 
• 541-41-3 chloroformic acid ethyl ester 
• 88962-42-9 N-Benzyloxycarbonyl-L-isoleucyl-L-phenylalanin-2-iodethylester 
• 22951-98-0 H-Ile-Phe-OH 
• 67-56-1 methanol 
• 63-91-2 L-phenylalanine 
• 25529-36-6 Z-Ile-OPfp 
• 501-53-1 benzyl chloroformate 
• 88962-26-9 L-phenylalanine 2-bromoethyl ester hydrochloride 
• 88962-33-8 N-Benzyloxycarbonyl-L-isoleucyl-L-phenylalanin-2-bromethylester 
• 16874-17-2 L-phenylalanine tert-butyl ester 

Downstream Products

• 1027905-53-8 (S)-2-((2S,3S)-2-Benzyloxycarbonylamino-3-methyl-pentanoylamino)-3-phenyl-propionic acid 2,5-dioxo-pyrrolidin-1-yl ester 
• 945403-81-6 2'-N-(N-benzyloxycarbonyl-L-isoleucyl-L-phenylalanyl)-amino-2'-deoxy-3',5'-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-adenosine 
• 945403-82-7 2'-N-(N-benzyloxycarbonyl-L-isoleucyl-L-phenylalanyl)-amino-2'-deoxyadenosine 

Relevant articles and documents

Formation and isolation of simple, stable, acyclic di- and tripeptide hemiacetals

Di- and tripeptide aldehydes were found to undergo reaction with methanol to afford the corresponding methyl hemiacetals. These compounds, which possessed unusual stability, were isolated and characterized using NMR techniques and a chemical correlation experiment.

Peptide synthesis in aqueous solution. IV. Preparation and properties of [p-(benzyloxycarbonyloxy)phenyl]dimethylsulfonium methyl sulfate, [p-(t-butoxycarbonyloxy)phenyl]dimethylsulfonium methyl sulfate and [p-(9-fluorenylmethyl-oxycarbonyloxy)phenyl]dimethylsulfonium methyl sulfate as water-soluble N-acylating reagents

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