132575-63-4 Usage
Description
(3aR,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyldihydro-3aH-cyclopenta[d][1,3]dioxol-4(5H)-one is a chiral cyclic ether compound with a molecular formula of C10H16O4. It features a cyclopentane ring fused to a dioxolane ring and a hydroxymethyl group attached to the cyclopentane ring. (3aR,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyldihydro-3aH-cyclopenta[d][1,3]dioxol-4(5H)-one contains a ketone functional group and has a non-superimposable mirror image, indicating its chiral nature. Its potential applications may lie in organic synthesis, pharmaceuticals, or as a building block for more complex molecules, with its specific uses depending on its stereochemistry and the reactions it can participate in.
Uses
Used in Organic Synthesis:
(3aR,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyldihydro-3aH-cyclopenta[d][1,3]dioxol-4(5H)-one is used as a building block for the synthesis of more complex organic molecules, leveraging its unique cyclic structure and functional groups to create a variety of compounds with different properties and applications.
Used in Pharmaceutical Industry:
As a chiral molecule, (3aR,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyldihydro-3aH-cyclopenta[d][1,3]dioxol-4(5H)-one may be utilized in the development of pharmaceuticals, where its specific stereochemistry could play a crucial role in the compound's biological activity and selectivity towards target proteins or enzymes.
Used in Research and Development:
(3aR,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyldihydro-3aH-cyclopenta[d][1,3]dioxol-4(5H)-one serves as a valuable research tool for studying the effects of stereochemistry on molecular interactions and reactivity. It can be used to investigate asymmetric synthesis, enzymatic reactions, and the development of new methodologies for the production of enantiomerically pure compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 132575-63-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,2,5,7 and 5 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 132575-63:
(8*1)+(7*3)+(6*2)+(5*5)+(4*7)+(3*5)+(2*6)+(1*3)=124
124 % 10 = 4
So 132575-63-4 is a valid CAS Registry Number.
132575-63-4Relevant articles and documents
PRMT5 INHIBITORS
-
Page/Page column 35; 50, (2020/03/02)
The present invention provides a compound of Formula (I) or the pharmaceutically acceptable salts thereof, which are PRMT5 inhibitors.
A General Biomimetic Hetero-Diels-Alder Approach to the Core Skeletons of Xenovulene A and the Sterhirsutins A and B
Li, Pei-Jun,Dr?ger, Gerald,Kirschning, Andreas
, p. 998 - 1001 (2019/02/14)
A biomimetic, regio- and stereoselective approach to the 5,6,11-tricyclic core skeleton of xenovulene A, as well as sterhirsutins A and B, is described. The key steps are a biomimetic inverse-electron-demand hetero-Diels-Alder cycloaddition of α-humulene and a ribose-derived vinyl ketone, followed by acid-catalyzed rearrangement of the 1,3-dioxolane that neighbors the resultant cyclic enol ether.
Synthesis of 1α-Pyrophosphoryl-2α,3α-dihydroxy-4β-cyclopentanemethanol-5-phosphate, a Carbocyclic Analog of 5-Phosphoribosyl-1-pyrophosphate (PRPP)
Parry, Ronald J.,Haridas, Kochat
, p. 7013 - 7016 (2007/10/02)
5-Phosphoribosyl-1-pyrophosphate- (PRPP) is a key intermediate in a variety of important metabolic pathways.A total synthesis of the cyclopentyl analog of PRPP has been accomplished.A formal total synthesis of the enantiomer of this analog whose absolute
