132585-06-9Relevant articles and documents
4-(5-PHENYL-1,3,4-OXADIAZOL-2-YL)BIPHENYL-4'-CARBOXYLIC ACID: ITS FUNCTIONAL DERIVATIVES AND THEIR HETEROCYCLIZATION INTO 1,3-THIAZINE-6-THIONES
Kurfuerst, Antonin,Kuthan, Josef,Lhotak, Pavel,Nadenik, Petr,Schroth, Werner,Spitzner, Roland
, p. 2722 - 2730 (2007/10/02)
The title carboxylic acid II prepared by hypobromide oxidation of 4'-acetyl derivative I was converted into its functional derivatives III-IX by standard preparative procedures.The C-acylation of 1,1-dichloroethene with acyl chloride III gave dichloroethenyl ketone X affording 2,4-disubstituted 1,3-thiazine-6-thiones XIa-XIe and XII by cyclocondensations with appropriate thioamides.The reactivity of heterocycles XIb, XIc was checked by their conversion into the expected products XIII-XV.IR and NMR spectroscopic patterns of the new prepared compounds are discussed.