1326317-04-7Relevant articles and documents
Designing nonsaccharide, allosteric activators of antithrombin for accelerated inhibition of factor Xa
Al-Horani, Rami A.,Liang, Aiye,Desai, Umesh R.
, p. 6125 - 6138 (2011/10/30)
Antithrombin is a key regulator of coagulation and prime target of heparins, clinically used anticoagulants. Heparins induce a two-step conformational activation of antithrombin, a process that has remained challenging to target with molecules devoid of t